A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice

Raup-Konsavage Wesley M.; Cooper Timothy K.; Yochum Gregory S.

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A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice

机译：MYC在DSS诱导的小鼠损伤后锂刺激结肠上皮细胞修复中的作用。

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Chronic inflammation disrupts the colonic epithelial layer in patients afflicted by ulcerative colitis (UC). The use of inhibitors of glycogen synthase kinase three beta (GSK3 beta) has proven efficacious to mitigate disease symptoms in rodent models of UC by reducing the pro-inflammatory response. Less is known about whether these inhibitors promote colonic regeneration by stimulating proliferation of colonic epithelial cells.

机译：慢性炎症破坏了溃疡性结肠炎（UC）患者的结肠上皮层。糖原合酶激酶三β（GSK3 beta）抑制剂的使用已被证明可通过减少促炎反应来减轻UC啮齿动物模型中的疾病症状。关于这些抑制剂是否通过刺激结肠上皮细胞增殖来促进结肠再生知之甚少。

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《Digestive Diseases and Sciences》 |2016年第2期|共13页
作者
Raup-Konsavage Wesley M.; Cooper Timothy K.; Yochum Gregory S.;
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正文语种 eng
中图分类消化系及腹部疾病;
关键词
Ulcerative colitis; MYC; Glycogen synthase kinase; Lithium; Colonic regeneration;

机译：溃疡性结肠炎;MYC;糖原合酶激酶;锂;结肠再生;

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1. A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice [J] . Raup-Konsavage Wesley M., Cooper Timothy K., Yochum Gregory S. Digestive Diseases and Sciences . 2016,第2期

机译：MYC在DSS诱导的小鼠损伤后锂刺激结肠上皮细胞修复中的作用。
2. Astaxanthin Has a Potential Role in Antioxidation and Oxidative Damage Repair in UVC Irradiated Mice [J] . Ni Yinhua, Ma Lingyan, Wu Lianxin, Biology Bulletin . 2018,第6期

机译：虾青素在UVC辐照小鼠的抗氧化和氧化损伤修复中具有潜在作用
3. GCSF Partially Repairs Heart Damage Induced by Repetitive β-adrenergic Stimulation in Mice: Potential Role of the Mobilized Bone Marrow-derived Cells [J] . B. Nieto-Lima, A. Cano-Martinez, G. Zarco-Olvera, International Journal of Pharmacology . 2016,第7期

机译：GCSF部分修复小鼠重复性β-肾上腺素能刺激引起的心脏损害：动员的骨髓衍生细胞的潜在作用
4. Imaging living hair cells within the cochlear epithelium of mice using two-photon microscopy [C] . Tao Yuan, Simon S. Gao, Peter Saggau, Imaging, manipulation, and analysis of biomolecules, cells, and tissues VII . 2009

机译：使用双光子显微镜对小鼠耳蜗上皮中的活毛细胞进行成像
5. The role of the enzyme cyclooxygenase and bile in the damage and repair of intestinal epithelium. [D] . Campbell, Nigel Brent. 2003

机译：环氧合酶和胆汁酶在肠上皮损伤和修复中的作用。
6. Metabolomics reveals aging-associated attenuation of noninvasive radiation biomarkers in mice: potential role of polyamine catabolism and incoherent DNA damage-repair [O] . Soumen K. Manna, Kristopher W. Krausz, Jessica A. Bonzo, -1

机译：代谢组学揭示了小鼠中非侵入性辐射生物标记物的衰老相关衰减：多胺分解代谢和不连贯的DNA损伤修复的潜在作用
7. The role of vitamin D3 administration on IFN-γ, IL-1β expression and repair of colonic mucosa at mice models of ulcerative colitis [O] . Wenny Prafitriyanti, Satrio Wibowo, Eko Sulistijono 2021

机译：维生素D3给药对溃疡性结肠炎小鼠模型的IFN-γ，IL-1β表达和结肠粘膜表达和修复的作用

A Role for MYC in Lithium-Stimulated Repair of the Colonic Epithelium After DSS-Induced Damage in Mice

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