Emerging DNA sequencing technologies for human genomic medicine.

Strausberg RL; Levy S; Rogers YH

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Emerging DNA sequencing technologies for human genomic medicine.

机译：用于人类基因组医学的新兴DNA测序技术。

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The completion of draft sequences of the human genome represented a remarkable achievement for automated DNA sequencing based on Sanger technology. However, the future requires substantial leaps in sequencing technology such that whole genome sequencing will become a standard component of biomedical research and patient care. In this review we describe current advances that are in early stages of development, but that point toward technology that will enable the onset of genomic medicine encompasses strategies for preventative medicine and intervention based on complete knowledge of an individual's genome.

机译：人类基因组草图序列的完成代表了基于Sanger技术的自动DNA测序的非凡成就。然而，未来需要测序技术的飞跃，以便全基因组测序将成为生物医学研究和患者护理的标准组成部分。在这篇综述中，我们描述了处于开发早期阶段的当前进展，但是指向将使基因组医学发作的技术指向基于个人基因组的全面知识的预防医学和干预策略。

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《Drug discovery today》 |2008年第14期|共9页
作者
Strausberg RL; Levy S; Rogers YH;
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正文语种 eng
中图分类药学;
关键词
Medicine; Human; Genome; DNA; 医学; 基因组;

机译：Medicine;Human;Genome;DNA;医学;基因组;

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1. Emerging DNA sequencing technologies for human genomic medicine. [J] . Strausberg RL, Levy S, Rogers YH Drug discovery today . 2008,第13a14期

机译：用于人类基因组医学的新兴DNA测序技术。
2. Emerging genomic technologies and the concept of personalized medicine. [J] . Glinskii VG, Glinsky GV Cell cycle . 2008,第15期

机译：新兴的基因组技术和个性化医学概念。
3. Attomole-level Genomics with Single-molecule Direct DNA, cDNA and RNA Sequencing Technologies [J] . Ozsolak Fatih Current Issues in Molecular Biology . 2016,第Null期

机译：具有单分子直接DNA，cDNA和RNA测序技术的原子级基因组学
4. Targeted profiling of 5-(hydroxy)methylcytosine in genomic DNA from human livers: Next-generation sequencing of target enriched DNA reveals unexpectedly high interindividual variability of cytosine methylation and hydroxymethylation [C] . Ivanov Maxim, Ingelman-Sundberg Magnus, Kals Mart, IEEE International Conference on Bioinformatics and Biomedicine . 2014

机译：人类肝脏基因组DNA中5-（羟）甲基胞嘧啶的靶向分析：富含靶DNA的下一代测序揭示了胞嘧啶甲基化和羟甲基化的意料之外的高度个体差异
5. Exploring the Genomic Basis of Traits Relevant to Evolution and Ecology of Chestnut (Castanea) Using High-throughput DNA Sequencing and Bioinformatics [D] . LaBonte, Nicholas R. 2017

机译：利用高通量DNA测序和生物信息学探索与栗子（Castanea）的演化和生态学相关性状的基因组
6. Pursuing Advances in DNA Sequencing Technology to Solve a Complex Genomic Jigsaw Puzzle: The Agglutinin-Like Sequence (ALS) Genes of Candida tropicalis [O] . Soon-Hwan Oh, Allyson Isenhower, Rubi Rodriguez-Bobadilla, 2020

机译：追求DNA测序技术的进步解决复杂的基因组拼图：念珠菌的氨基蛋白样序列（ALS）基因
7. Emerging technologies in DNA sequencing [O] . M. L. Metzker 2005

机译：DNA测序中的新兴技术
8. DNA Sequencing Technologies within the Chemical and Biological Defense Enterprise: How to Position the Department of Defense to Maximize the Use of These Emerging Technologies - JUPITR. [R] . Hirschberg, D. L., Betts, K., Hutchins, R., 2015

机译：化学和生物防御企业中的DNa测序技术：如何定位国防部以最大限度地利用这些新兴技术 - JUpITR。

Emerging DNA sequencing technologies for human genomic medicine.

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