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首页> 外文期刊>Drug discovery today >New drugs from ancient natural foods. Oleocanthal, the natural occurring spicy compound of olive oil: a brief history
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New drugs from ancient natural foods. Oleocanthal, the natural occurring spicy compound of olive oil: a brief history

机译：来自古代天然食品的新药。 Oleocanthal，橄榄油的天然辛辣成分：简史

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摘要

Extra-virgin olive oil (EVOO), a principal component of the Mediterranean diet (Med diet), is one of the most ancient known foods and has long been associated with health benefits. Many phenolic compounds extracted from Olea europea L. have attracted attention since their discovery. Among these phenolic constituents, oleocanthal has recently emerged as a potential therapeutic molecule for different diseases, showing relevant pharmacological properties in various pathogenic processes, including inflammation, cancers and neurodegenerative diseases. Here, we discuss and summarize the most recent pharmacological evidence for the medical relevance of oleocanthal, focusing our attention on its anti-inflammatory and chemotherapeutic roles.
机译：特级初榨橄榄油（EVOO）是地中海饮食（地中海饮食）的主要成分，是最古老的已知食品之一，长期以来一直与健康有关。自发现以来，从油橄榄中提取的许多酚类化合物引起了人们的关注。在这些酚类成分中，油橄榄酚最近已成为各种疾病的潜在治疗分子，在包括炎症，癌症和神经退行性疾病在内的各种致病过程中均显示出相关的药理特性。在这里，我们讨论并总结了有关油橄榄的医学相关性的最新药理学证据，并将我们的注意力集中在其抗炎和化学治疗作用上。

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