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Lymphogranuloma venereum, where do we stand?: clinical recommendations.

机译:性病淋巴肉芽肿,我们站在哪里?:临床建议。

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摘要

Lymphogranuloma venereum (LGV) was formerly known as a sexually transmissible infection confined to equatorial regions, but also as an "imported" sexually transmissible infection in the Western world. However, since 2003, with the first cases of LGV proctitis among men who have sex with men reported in the Netherlands, an ongoing epidemic has been revealed in Western society dating back to at least 1981. In this article a case of LGV proctitis is presented, and the state of the art diagnostics, treatment and common complications concerning LGV are discussed. Moreover, risk factors and the background of the recent epidemic of LGV in the Western world among men who have sex with men are summarized. There is a need to develop new diagnostic assays, to prevent complications and to protect the community from more expansive transmission. Shorter antibiotic treatment courses for LGV are necessary but require large controlled clinical trials. The microbial and immunological background of LGV infection in relation to HIV should be studied in detail and could help to explain the considerable number of asymptomatic LGV cases.
机译:性病淋巴肉芽肿(LGV)以前被称为性传播感染,仅限于赤道地区,但在西方世界也被称为“进口”性传播感染。但是,自2003年以来,荷兰报道了首例与男性发生性行为的男性LGV直肠炎,西方社会至少在1981年就开始流行这种流行病。本文介绍了LGV直肠炎一例。 ,并讨论了有关LGV的最新诊断,治疗方法和常见并发症。此外,总结了与男性发生性关系的男性的危险因素和西方世界最近LGV流行的背景。需要开发新的诊断方法,以防止并发症并保护社区免受更广泛的传播。 LGV较短的抗生素治疗课程是必要的,但需要进行大规模的对照临床试验。应详细研究与HIV相关的LGV感染的微生物学和免疫学背景,可以帮助解释大量无症状LGV病例。

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