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The staying power of canine viral enteritis

机译:犬病毒性肠炎的持久力

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摘要

Strains of canine parvovirus and coronavirus are evolving, so the diseases they cause still persist. But through proper hygiene and vaccination, dogs can be protected. Three decades ago, canine viral enteritis became prominent in dog populations and veterinary clinics worldwide. At that time, we knew we were dealing with an acute disease syndrome characterized by vomiting, lethargy, and diarrhea that was sometimes hemorrhagic, especially in young puppies. (After multi-aged dogs succumbed in the initial epizootic, the disease was primarily concentrated in puppies younger than 6 months old.) Researchers discovered two primary etiologic agents, canine parvovirus type 2 (CPV-2) and canine coronavirus (CCV). In addition, the disease appeared to demonstrate a seasonal prevalence for CPV-2 (summer and fall) and CCV (winter and spring). With knowledge of the viral pathogenesis and host immunity, vaccines were developed in an attempt to control the disease. While these preventive measures were somewhat successful, we still encounter canine viral enteritis today.
机译:犬细小病毒和冠状病毒株正在进化,因此它们引起的疾病仍持续存在。但是通过适当的卫生和疫苗接种,可以保护狗。三十年前,犬病毒性肠炎在世界各地的犬只和兽医诊所中变得很突出。那时,我们知道我们正在应对一种以呕吐,嗜睡和腹泻为特征的急性疾病综合症,有时会出血,尤其是在幼犬中。 (多头犬死于最初的流行病后,该病主要集中在6个月以下的幼犬中。)研究人员发现了两种主要的病原体,即2型犬细小病毒(CPV-2)和犬冠状病毒(CCV)。此外,该病似乎表现出CPV-2(夏季和秋季)和CCV(冬季和春季)的季节性流行。在了解病毒的发病机理和宿主免疫力的基础上,开发了疫苗以控制疾病。尽管这些预防措施取得了一定的成功,但今天我们仍然遇到犬病毒性肠炎。

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