Bupropionaltrexone fixed-dose combination for the treatment of obesity.

Halpern B; Faria AM; Halpern A

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Bupropionaltrexone fixed-dose combination for the treatment of obesity.

机译：安非他酮/纳曲酮固定剂量组合治疗肥胖症。

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The combination of bupropion and naltrexone is one of the most promising new possibilities for the treatment of obesity in an era of increasing prevalence of this disease and decreasing options for its pharmacological management. Although approved by FDA panel members, it was temporally rejected by the FDA afterwards, who demanded more cardiovascular safety data for its commercialization. This monograph will focus on the physiology involved in its mechanisms of action and results of clinical trials.

机译：在该疾病的患病率上升和药物治疗选择减少的时代，安非他酮和纳曲酮的组合是治疗肥胖症最有希望的新方法之一。尽管已获得FDA小组成员的批准，但此后暂时被FDA拒绝，因为FDA要求获得更多的心血管安全性数据以使其商业化。该专着将着重于其作用机理和临床试验结果所涉及的生理学。

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《Drugs of today: Medicamentos de actualidad》 |2011年第8期|共7页
作者
Halpern B; Faria AM; Halpern A;
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正文语种 eng
中图分类药学;
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机译：安非他酮/纳曲酮固定剂量组合治疗肥胖症。
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Bupropionaltrexone fixed-dose combination for the treatment of obesity.

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