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首页> 外文期刊>Drug and alcohol review >Injecting buprenorphine-naloxone film: Findings from an explorative qualitative study
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Injecting buprenorphine-naloxone film: Findings from an explorative qualitative study

机译：注射丁丙诺啡-纳洛酮薄膜：一项探索性定性研究的发现

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Introduction and Aims. Experiences of buprenorphine-naloxone (BNX) sublingual film injection are not well documented or understood. We examined how people who inject BNX film seek and share information about this practice, document the methods used to prepare BNX film for injection, and report participants' experiences of this practice. Design and Methods. Interviews were (n = 16) conducted with people who indicated that they had injected BNX film since its introduction onto the Australian market. Semistructured interviews were recorded and transcribed. NVivo10 program (QSR International) was used to analyse the data using qualitative description methodology. Results. Participants largely reported similar BNX film preparation techniques, although the texture of BNX film during preparation to inject was reported to be unusual (gluggy), and there were many varied accounts associated with the amount of water used. Physical harms reported as associated with injecting BNX film were described (including local and systemic issues); participants reported injecting the film to enhance its immediate effects, yet generally reported that sublingual administration provided longer-lasting effects. Discussion and Conclusions. Understanding knowledge acquisition about injecting new formulations of opioid substitution therapy is crucial in developing more effective harm-reduction strategies. Dissemination by peer networks to those who are currently or planning to inject BNX film regarding the 'gelatine like' texture when mixing, using only cold water and double filtering is important to ensure safer injecting practices. Findings from this study highlight the importance of peer networks for the dissemination of harm-reduction information. Introduction of new formulations internationally requires more qualitative studies to inform safer practices.
机译：简介和目的。丁丙诺啡-纳洛酮（BNX）舌下薄膜注射的经验尚未得到充分记载或了解。我们研究了注射BNX胶片的人如何寻求和分享有关此实践的信息，记录了制备BNX胶片用于注射的方法，并报告了参与者对该实践的经验。设计和方法。采访（n = 16）的人表示，自从BNX胶片引入澳大利亚市场以来，他们已经注射了BNX胶片。记录并抄录半结构化访谈。 NVivo10程序（QSR International）用于使用定性描述方法分析数据。结果。尽管据报道，在准备注射过程中BNX膜的质地不寻常（发粘），但参加者在很大程度上报告了类似的BNX膜制备技术，并且有许多与用水量有关的说法。描述了与注射BNX胶片有关的身体伤害（包括局部和系统性问题）;参与者报告了注射该胶卷以增强其即时效果，但总体上报告称舌下给药可提供更持久的效果。讨论和结论。了解有关注射阿片类药物替代疗法新制剂的知识获取对于制定更有效的减少伤害策略至关重要。通过对等网络向当前或计划在混合时注射有关“明胶样”质地的BNX胶片的人们传播，仅使用冷水和双重过滤对于确保更安全的注射操作很重要。这项研究的结果突出了对等网络对于传播减少伤害信息的重要性。在国际上引入新配方需要进行更多的定性研究，以提供更安全的做法。

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