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首页> 外文期刊>Drug and alcohol review >The association between cocaine use and short-term outcomes for the treatment of heroin dependence: findings from the Australian Treatment Outcome Study (ATOS).
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The association between cocaine use and short-term outcomes for the treatment of heroin dependence: findings from the Australian Treatment Outcome Study (ATOS).

机译：可卡因的使用与海洛因依赖治疗的短期结果之间的关联：澳大利亚治疗结果研究（ATOS）的发现。

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摘要

The aim of this study was to determine the prevalence of cocaine use among individuals presenting for treatment for heroin dependence, describe the clinical profile of heroin users who also use cocaine and to establish the effects of cocaine use on short term outcomes for the treatment for heroin dependence. A longitudinal follow-up of 549 heroin users recruited in Sydney for the Australian Treatment Outcome Study was conducted at 3-month post-baseline interview. At baseline, current cocaine use was common (39%) and was associated with increased drug use, needle risk taking and criminality. The 3-month prevalence of cocaine use declined significantly to 19%. Thirty-five per cent of those who had used cocaine at baseline continued to use at 3 months, while 9% of the sample had commenced cocaine use. Those who entered residential rehabilitation at baseline were less likely than other treatment entrants and the non-treatment group to have used cocaine at follow-up. Treatment retention was not affected by baseline cocaine use status; however, baseline cocaine users (CU) displayed higher levels of heroin use, polydrug use and drug-related problems. A poorer outcome was associated with the commencement or continuation of cocaine use, while cessation of cocaine use resulted in significant improvements on these measures. Cocaine use was common among individuals seeking treatment for heroin dependence and was an important moderator of treatment outcome. It appears that cocaine use has a strong negative effect on treatment outcome over and above that caused by polydrug use generally.
机译：这项研究的目的是确定在接受海洛因依赖治疗的个体中可卡因的使用率，描述也使用可卡因的海洛因使用者的临床概况，并确定可卡因的使用对短期治疗海洛因的影响依赖。在基线后3个月的访谈中，对在悉尼招募用于澳大利亚治疗结果研究的549名海洛因使用者进行了纵向随访。在基线时，当前可卡因的使用很普遍（39％），并且与药物使用增加，针头冒险和犯罪行为有关。可卡因使用的3个月流行率显着下降至19％。在基线使用可卡因的人中有35％的人在3个月后继续使用可卡因，而有9％的样本已开始使用可卡因。在基线时进入住所康复的人比其他治疗进入者和非治疗组在随访中使用可卡因的可能性要小。可卡因基线使用状态不受治疗保留的影响;但是，可卡因基线使用者（CU）的海洛因使用，多药使用和与毒品有关的问题水平较高。可卡因使用开始或持续使用的结果较差，而停止使用可卡因则导致这些措施的显着改善。可卡因的使用在寻求海洛因依赖治疗的个体中很常见，并且是治疗结果的重要调节剂。似乎可卡因的使用对治疗结果的负面影响比一般多药物使用引起的影响要大。

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