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首页> 外文期刊>Drug and alcohol review >Hepatitis B immunity in a population of drug and alcohol users.
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Hepatitis B immunity in a population of drug and alcohol users.

机译：吸毒和酗酒的人群中的乙型肝炎免疫力。

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摘要

The objective of this study was to determine the level of immunity from Hepatitis B infection in an Australian population of drug and alcohol users, and the validity of self-reported immune status. A cross-sectional survey was employed of drug and alcohol users presenting for treatment, who were clients of De Paul House, a community-based drug and alcohol withdrawal service in Victoria. Outcome measures were: hepatitis B serology and personal reports of hepatitis B immunity. A total of 118 people were enrolled; 22% were injecting drug users and 48% reported past injecting drug use, while 55% were alcohol users; 51% had no general practitioner; 73% of participants were unaware of whether they were protected from hepatitis B infection, while 19.5% believed they were protected. However, serology demonstrated that 52.2% of those who believed they were protected were not immune. Only 21% of participants were immune. This is the first study in an Australian setting since the 1970s to examine the effectiveness of vaccination targeted to this population, and demonstrates low rates of immunity. New strategies are needed to deliver vaccination to this group. These will need to take account of the often chaotic nature of their lives, the poor validity of self-reported immunity, and the lack of primary care links.
机译：这项研究的目的是确定澳大利亚吸毒和酗酒人群中乙型肝炎感染的免疫水平，以及自我报告的免疫状态的有效性。一项横断面调查针对的是正在接受治疗的毒品和酒精使用者，他们是维多利亚社区的戒毒服务机构De Paul House的客户。结果指标为：乙肝血清学和乙肝免疫力的个人报告。共有118人报名;注射吸毒者占22％，过去注射吸毒者占48％，而酒精滥用者占55％; 51％没有全科医生; 73％的参与者不知道自己是否受到乙肝感染的保护，而19.5％的参与者则认为自己受到了保护。但是，血清学证明，认为自己受到保护的人中有52.2％的人没有免疫力。只有21％的参与者免疫。这是自1970年代以来在澳大利亚开展的第一项研究，目的是检查针对该人群的疫苗接种的有效性，并证明免疫率低。需要新的策略为该人群提供疫苗接种。这些将需要考虑到他们生活中经常混乱的性质，自我报告的免疫有效性低下以及缺乏初级保健联系。

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