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Chronic fatigue syndrome: probable pathogenesis and possible treatments.

机译:慢性疲劳综合征:可能的发病机制和可能的治疗方法。

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摘要

Chronic fatigue syndrome (CFS) belongs in the medically unexplained illnesses. It affects approximately 0.2-0.7% of the population in Western countries. It is characterised by unexplained fatigue, lasting 6 months or more, impairment of neurocognitive functions and quality of sleep, and of somatic symptoms, such as recurrent sore throat, muscle aches, arthralgias, headache and postexertional malaise. No link between infections and CFS has been clearly established but the immune system is activated, there are aberrations in several hypothalamic-pituitary axes and involvement of other parts of the central nervous system. No specific treatment has been found. Cognitive behavioural therapy is established to be of value to improve quality of life. More effective treatment should result, as advances in biomedical as well as psychological research continue.
机译:慢性疲劳综合症(CFS)属于医学上无法解释的疾病。它影响了西方国家约0.2-0.7%的人口。它的特征是无法解释的疲劳,持续6个月或更长时间,神经认知功能和睡眠质量受损,以及躯体症状,如反复出现的咽痛,肌肉酸痛,关节痛,头痛和劳累乏力。感染与CFS之间没有明确的联系,但免疫系统已激活,下丘脑-垂体轴的多个畸变以及中枢神经系统其他部位的受累。尚未发现具体治疗方法。认知行为疗法被认为具有改善生活质量的价值。随着生物医学和心理学研究的不断发展,应产生更有效的治疗方法。

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