Pharmacogenetics: Yeast lead the way

Foss E; Bedalov A

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Pharmacogenetics: Yeast lead the way

机译：药物遗传学：酵母引领

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In this issue of Chemistry & Biology, Perlstein et al. [1] use genetically diverse strains of yeast to study the genetic basis of differences in cellular responses to small molecules. Their results suggest that drug responses are regulated by a limited number of loci, and that this system can identify clusters of functionally similar molecules.

机译：在本期《化学与生物学》中，Perlstein等人。 [1]使用遗传多样的酵母菌株研究细胞对小分子反应差异的遗传基础。他们的结果表明，药物反应受数量有限的基因座调控，并且该系统可以识别功能相似的分子簇。

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《Chemistry & biology》 |2006年第3期|共3页
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Foss E; Bedalov A;
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1. Pharmacogenetics: Yeast lead the way [J] . Foss E, Bedalov A Chemistry & biology . 2006,第3期

机译：药物遗传学：酵母引领
2. ABCB1 variant provides important leads for pharmacogenetics of epilepsy [J] . PhaniM., SatyamoorthyK. Journal of postgraduate medicine . 2014,第3期

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3. PHARMACOGENETIC DIRECTED DOSING LEADS TO OPTIMIZED VORICONAZOLE LEVELS IN PEDIATRIC PATIENTS RECEIVING HEMATOPOIETIC STEM CELL TRANSPLANTS [J] . Teusink Ashley, Vinks Alexander, Zhang Kejian, Pediatric blood & cancer . 2014,第Suppla1期

机译：接受造血干细胞移植的小儿患者的药动学定向给药剂量可优化左旋唑水平
4. Characterization of Heavy Metals Resistant Yeast Isolated from Activated Sludge in Rungkut, Surabaya, Indonesia as Biosorbent of Mercury, Copper, and Lead [C] . Wahyu Irawati, Yantra Wijaya, Salomo Christian, International Conference on Biological Science . 2016

机译：从跑克特，泗水，印度尼西亚的活性污泥中分离的重金属抗性酵母的特征作为汞，铜和铅的生物吸附剂
5. Fusion of inverted repeats leads to formation of dicentric chromosomes that cause genome instability in budding yeast. [D] . Kaochar, Salma. 2010

机译：反向重复序列的融合导致形成双着丝粒染色体，从而导致发芽酵母中的基因组不稳定。
6. Serial enzymatic hydrolysis of cell walls of two serotypes of yeast-form Histoplasma capsulatum with alpha(1 leads to 3)-glucanase beta(1 leads to 3)-glucanase pronase and chitinase. [O] . E Reiss 1977

机译：两种血清型酵母形式的荚膜胞浆菌的两种血清型的细胞壁的系列酶促水解反应其中α（1导致3）-葡聚糖酶β（1导致3）-葡聚糖酶链霉蛋白酶和几丁质酶。
7. Pharmacogenetics: Yeast Lead the Way [O] . Foss Eric, Bedalov Antonio 2006

机译：药物遗传学：酵母引领潮流

Pharmacogenetics: Yeast lead the way

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