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首页> 外文期刊>Drug and alcohol dependence >Knowledge of HIV seropositivity is a predictor for initiation of illicit drug use: incidence of drug use initiation among female sex workers in a high HIV-prevalence area of China.
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Knowledge of HIV seropositivity is a predictor for initiation of illicit drug use: incidence of drug use initiation among female sex workers in a high HIV-prevalence area of China.

机译:艾滋病毒血清阳性的知识是开始非法吸毒的一个预测因素:在中国艾滋病毒高发地区,女性性工作者开始吸毒的发生率。

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BACKGROUND: Drug use and sex work have had facilitative roles in the transmission of HIV/AIDS in China. Stopping drug use among sex workers may help to control the growth of the HIV/AIDS epidemic among Chinese sex workers. METHODS: From March 2006 to November 2009, female sex workers (FSW) in Kaiyuan City, Yunnan, China were recruited into an open cohort study. Participants were interviewed and tested for drug use and HIV/sexually transmitted infection (STI) prevalence. Follow-up surveys were conducted every six months. Multivariate Cox proportional hazards regression model with time dependent variables was used to measure the associations between independent variables and drug initiation. RESULTS: During the course of the study, 66 (8.8%) FSWs initiated drug use yielding an overall incidence of 6.0 per 100 person years (PY) (95% confidence interval [CI], 4.67-7.58). In the multivariate Cox proportional hazards regression model, being HIV-positive and aware of positive serostatus (adjusted hazard ratio [AHR] 2.6, 95% CI 1.24-5.55), age at initiation of commercial sex work <20 years (AHR 1.8, 95% CI 1.12-3.01), and working in a high-risk establishment (AHR 1.9, 95% CI 1.14-3.04) were associated with illicit drug initiation. CONCLUSIONS: Being HIV-positive and aware of positive serostatus was the most salient predictor for the initiation of illicit drug use. Interventions offering sources of education, treatment, support, and counseling to HIV-positive FSWs need to be implemented in order to help promote self-efficacy and safe behaviors among this group of high-risk women.
机译:背景:吸毒和性工作在中国艾滋病毒/艾滋病的传播中具有促进作用。在性工作者中停止使用毒品可能有助于控制中国性工作者中艾滋病毒/艾滋病的流行。方法:从2006年3月至2009年11月,招募了中国云南省开远市的女性性工作者(FSW)进行公开队列研究。对参加者进行了采访并进行了药物使用和HIV /性传播感染(STI)患病率测试。每六个月进行一次跟踪调查。具有时间相关变量的多元Cox比例风险回归模型用于测量独立变量与药物启动之间的关联。结果:在研究过程中,有66(8.8%)名FSW开始吸毒,每100人年(PY)的总发生率为6.0(95%置信区间[CI],4.67-7.58)。在多变量Cox比例风险回归模型中,艾滋病毒呈阳性,并了解阳性血清状况(调整后的危险比[AHR] 2.6,95%CI 1.24-5.55),从事商业性工作的年龄<20岁(AHR 1.8,95) %CI 1.12-3.01)和在高风险机构工作(AHR 1.9,95%CI 1.14-3.04)与非法药物的发起有关。结论:艾滋病毒呈阳性并且对阳性血清状态的了解是开始非法使用毒品的最明显的预测因素。需要实施干预措施,为艾滋病毒阳性的性工作者提供教育,治疗,支持和咨询资源,以帮助在这群高危妇女中促进自我效能和安全行为。

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