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首页> 外文期刊>Drug safety: An international journal of medical toxicology and drug experience >Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database
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Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database

机译:托伐普坦相关性肝损伤在常染色体显性多囊肾疾病患者中的临床表现:临床试验数据库分析

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摘要

Subjects with autosomal dominant polycystic kidney disease (ADPKD) who were taking tolvaptan experienced aminotransferase elevations more frequently than those on placebo in the TEMPO 3:4 (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) clinical trial.
机译:服用托伐普坦的常染色体显性遗传性多囊肾病(ADPKD)受试者在TEMPO 3:4(常染色体显性多囊性肾脏疾病及其结果管理中的托伐普坦功效和安全性)临床试验中经历的氨基转移酶升高频率高于安慰剂。

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