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首页> 外文期刊>JAIDS: Journal of acquired immune deficiency syndromes >Late-disease stage at presentation to an HIV clinic in the era of free antiretroviral therapy in Sub-Saharan Africa.
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Late-disease stage at presentation to an HIV clinic in the era of free antiretroviral therapy in Sub-Saharan Africa.

机译：在撒哈拉以南非洲地区免费抗逆转录病毒治疗时代，向艾滋病毒诊所就诊时处于晚期疾病阶段。

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BACKGROUND: Access to free antiretroviral therapy in sub-Saharan Africa has been steadily increasing, and the success of large-scale antiretroviral therapy programs depends on early initiation of HIV care. However, little is known about the stage at which those infected with HIV present for treatment in sub-Saharan Africa. METHODS: We conducted a cross-sectional analysis of initial visits to the Immune Suppression Syndrome Clinic of the Mbarara University Teaching Hospital, including patients who had their initial visit between February 2007 and February 2008 (N = 2311). RESULTS: The median age of the patients was 33 years (range 16-81 years), and 64% were female. More than one third (40%) were categorized as late presenters, that is, World Health Organization disease stage 3 or 4. Male gender, age 46-60 years (vs. younger), lower education level, being unemployed, living in a household with others, being unmarried, and lack of spousal HIV status disclosure were independently associated with late presentation, whereas being pregnant, having young children, and consuming alcohol in the prior year were associated with early presentation. CONCLUSIONS: Targeted public health interventions to facilitate earlier entry into HIV care are needed, as well as additional study to determine whether late presentation is due to delays in testing vs. delays in accessing care.
机译：背景：在撒哈拉以南非洲地区，免费获得免费的抗逆转录病毒疗法一直在稳步增长，大规模的抗逆转录病毒疗法计划的成功取决于早期的HIV护理。但是，对于在撒哈拉以南非洲接受治疗的艾滋病毒感染者的阶段知之甚少。方法：我们对Mbarara大学教学医院免疫抑制综合症诊所的初次就诊进行了横断面分析，包括在2007年2月至2008年2月之间初次就诊的患者（N = 2311）。结果：患者的中位年龄为33岁（范围16-81岁），其中64％为女性。超过三分之一（40％）的人被归类为晚期报告者，即世界卫生组织疾病3或4期。男性，年龄46-60岁（相对年轻），文化程度较低，失业，居住在与其他人的家庭，未婚和未透露配偶的HIV状况与晚期呈报独立相关，而孕妇，年幼的孩子和前一年饮酒与早期呈报相关。结论：需要有针对性的公共卫生干预措施，以促进较早地进入艾滋病毒治疗，还需要进行额外的研究，以确定是否迟到是由于测试延迟还是获得医疗服务的延迟。

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