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首页> 外文期刊>Japanese Journal of Ophthalmology >Effects of ocular rotation on parapapillary retinal nerve fiber layer thickness analysis measured with spectral-domain optical coherence tomography
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Effects of ocular rotation on parapapillary retinal nerve fiber layer thickness analysis measured with spectral-domain optical coherence tomography

机译：眼球旋转对光谱域光学相干断层扫描测量的乳头旁视网膜神经纤维层厚度分析的影响

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Purpose: To evaluate the effects of ocular rotation on parapapillary retinal nerve fiber layer (RNFL) thickness measured by spectral-domain optical coherence tomography (SD-OCT). Patients: and methods Eighty-eight normal and 205 glaucomatous eyes were studied. RNFL thickness was measured by 3D OCT. Ocular rotation angle was measured from a fundus image obtained by a non-mydriatic fundus camera equipped with 3D OCT. The average, hemi-superior, and hemi-inferior RNFL thicknesses as well as those in the 4 quadrants and the 16-segmented superotemporal (ST-1) and inferotemporal (IT-4) sectors were compared both before and after correcting for ocular rotation. Receiver operating characteristic curves and the areas under the curve (AUC) for the RNFL thicknesses were calculated on the basis of the data from glaucomatous and control eyes. The relationships between RNFL thickness and retinal sensitivity in the corresponding visual field were analyzed using a Humphrey field analyzer. Results: Correction for ocular rotation did not affect the AUCs of the hemi-superior and hemi-inferior RNFL thicknesses. RNFL thicknesses in all of the quadrants and in ST-1 and IT-4 were significantly changed by correcting for ocular rotation. The correlations between all RNFL sectors and retinal sensitivity were not changed by correcting for the ocular rotation angle. Conclusions: Ocular rotation compensation affected RNFL thickness measurement with 3D OCT. However, the effect was clinically negligible in the diagnosis of glaucoma.
机译：目的：评估眼球旋转对通过光谱域光学相干断层扫描（SD-OCT）测量的乳头状视网膜神经纤维层（RNFL）厚度的影响。患者：方法研究了88只正常眼和205只青光眼。 RNFL厚度通过3D OCT测量。从通过配备有3D OCT的非散瞳眼底照相机获得的眼底图像测量眼旋转角。在校正眼球旋转前后，比较了RNFL的平均，上半和下半RNFL厚度，以及在4个象限和16分割的颞颞（ST-1）和颞下（IT-4）区域的厚度。根据青光眼和对照眼的数据计算出RNFL厚度的接收器工作特性曲线和曲线下面积（AUC）。使用汉弗莱场分析仪分析了相应视野中RNFL厚度与视网膜敏感性之间的关系。结果：眼球旋转的矫正不影响上，下RNRF厚度的AUC。通过校正眼球旋转，所有象限以及ST-1和IT-4中的RNFL厚度均发生了显着变化。通过校正眼的旋转角度，所有RNFL扇区与视网膜敏感性之间的相关性均未改变。结论：眼球旋转补偿影响了3D OCT对RNFL厚度的测量。但是，在青光眼的诊断中该作用在临床上可以忽略不计。

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