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首页> 外文期刊>Circulation journal >Prevalence of Coronary Artery Disease in Japanese Patients With Cerebral Infarction -Impact of Metabolic Syndrome and Intracranial Large Artery Atherosclerosis-
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Prevalence of Coronary Artery Disease in Japanese Patients With Cerebral Infarction -Impact of Metabolic Syndrome and Intracranial Large Artery Atherosclerosis-

机译：日本脑梗死患者的冠状动脉疾病患病率-代谢综合征和颅内大动脉粥样硬化的影响-

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Background Patients with cerebral infarction have a high prevalence of asymptomatic coronary artery disease (CAD) and other vascular diseases, but there is a lack of such data for Japanese patients, so the present study investigated the prevalence of cardiovascular disease (CVD) in Japanese patients and determined the predictors of CAD. Methods and Results The study group comprised 104 patients with cerebral infarction who had no history of CVD. All patients underwent coronary computed tomographic angiography, and systematic evaluation was done on the basis of the presence of other vascular diseases, CVD risk markers, and the degree of atherosclerosis. Of the total, 39 patients (37.5%) had CAD, 9 (8.7%) had carotid artery stenosis, 9 (8.7%) had peripheral artery disease of the lower limbs, and 3 (2.9%) had atherosclerotic renal artery stenosis. Multiple regression analysis showed that the presence of CAD was independently associated with metabolic syndrome (odds ratio (OR) 5.008, 95% confidence interval (CI) 1.538-16.309; p<0.01) and intracranial large artery atherosclerosis (OR 4.979, 95%CI 1.633-15.183; p<0.01). Conclusion Japanese patients with cerebral infarction have a high prevalence of CVD, especially asymptomatic CAD. Both metabolic syndrome and intracranial large artery atherosclerosis may be potential predictors for identifying patients with cerebral infarction who are at the highest risk of asymptomatic CAD.
机译：背景技术脑梗死患者无症状性冠状动脉疾病（CAD）和其他血管疾病的患病率较高，但是对于日本患者而言缺乏此类数据，因此本研究调查了日本患者的心血管疾病（CVD）患病率并确定了CAD的预测因子。方法和结果研究组包括104例无CVD史的脑梗死患者。所有患者均接受了冠状动脉计算机断层血管造影，并根据其他血管疾病的存在，CVD危险标志物和动脉粥样硬化程度进行了系统评估。在所有患者中，有39例（37.5％）患有CAD，9例（8.7％）患有颈动脉狭窄，9例（8.7％）患有下肢外周动脉疾病，3例（2.9％）患有动脉粥样硬化性肾动脉狭窄。多元回归分析表明，CAD的存在与代谢综合征（比值比（OR）为5.008，95％置信区间（CI）为1.538-16.309; p <0.01）和颅内大动脉粥样硬化（OR为4.979，95％CI）独立相关1.633-15.183; p <0.01）。结论日本脑梗死患者的CVD患病率较高，尤其是无症状的CAD。代谢综合症和颅内大动脉粥样硬化均可能是识别无症状CAD风险最高的脑梗死患者的潜在预测指标。

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