...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Circulation journal >Carotid atherosclerosis as a risk factor for complex aortic lesions in patients with ischemic cerebrovascular disease.
【24h】

Carotid atherosclerosis as a risk factor for complex aortic lesions in patients with ischemic cerebrovascular disease.

机译：颈动脉粥样硬化是缺血性脑血管疾病患者复杂主动脉病变的危险因素。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Aortic arch atherosclerotic lesions can cause ischemic cerebrovascular disease (ICVD). The association between carotid and aortic atherosclerosis was examined, and it was investigated whether noninvasive carotid evaluation aids in the identification of aortic lesions as potential ICVD risk. The subjects comprised 147 patients with ICVD who had undergone carotid ultrasonography and transesophageal echocardiography. Carotid and aortic arch atherosclerosis was evaluated by measuring the maximum intima - media thickness (IMT), with aortic IMT of at least 4 mm, mobile plaques and/or ulcers defined as complex aortic lesions with potential ICVD risk. Carotid IMT was linearly associated with aortic IMT (r=0.53, p<0.001), and the association was independent of traditional cardiovascular risk factors (beta =0.36, p<0.001). Also, each 1 SD greater carotid IMT was associated with 4.2-fold (95% confidence interval: 2.5-7.0) higher likelihood of complex aortic lesions, with the likelihood little modified when controlling for cardiovascular risk factors. In particular, complex aortic lesions were found in 78% of patients with the highest carotid IMT tertile, compared with 14% of those with the lowest tertile (p<0.05). Based on these findings, carotid atherosclerosis is associated with aortic atherosclerosis, representing a risk factor for aortic lesions that are a potential ICVD risk.
机译：主动脉弓动脉粥样硬化病变可引起缺血性脑血管疾病（ICVD）。检查了颈动脉与主动脉粥样硬化之间的关联，并调查了无创颈动脉评估是否有助于将主动脉病变识别为潜在的ICVD风险。受试者包括147例接受了颈动脉超声检查和经食管超声心动图检查的ICVD患者。通过测量最大内膜-中膜厚度（IMT），主动脉IMT至少4 mm，活动斑块和/或溃疡定义为具有潜在ICVD风险的复杂主动脉病变来评估颈动脉和主动脉弓动脉粥样硬化。颈动脉IMT与主动脉IMT呈线性相关（r = 0.53，p <0.001），并且该关联独立于传统的心血管危险因素（β= 0.36，p <0.001）。同样，每增加1 SD的颈动脉IMT与复杂主动脉病变的可能性增加4.2倍（95％置信区间：2.5-7.0），并且在控制心血管危险因素时几乎没有改变。尤其是，在颈动脉IMT三元组最高的患者中发现了78％的患者具有复杂的主动脉病变，而三元组最低的患者中有14％的患者发现了主动脉病变（p <0.05）。基于这些发现，颈动脉粥样硬化与主动脉粥样硬化相关，代表主动脉病变的危险因素，这是潜在的ICVD风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号