...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Circulation journal >Association of body mass index, body fat, and weight gain with inflammation markers among rural residents in Japan.
【24h】

Association of body mass index, body fat, and weight gain with inflammation markers among rural residents in Japan.

机译：日本农村居民的体重指数，体脂和体重增加与炎症指标的关系。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Because obesity is thought to play a key role in atherosclerosis through the low-grade chronic inflammation, the present study was designed to investigate associations of body mass index (BMI), body fat, and weight gain with optimized inflammation markers in 1,053 residents who were 40 years of age and older from a rural community (total population = 3,940 in 2000) in Japan. People reporting having a cold and those who did not undergo blood examinations were excluded. C-reactive protein (CRP), fibrinogen, serum albumin, and white blood cell (WBC) count were used as the markers for inflammation, body fat was calculated by a conventional method, and weight change since the age of 20 was assessed. The BMI and body fat significantly increased with CRP quartile, and its correlation coefficients to BMI or body fat were relatively high. Similar associations were found for fibrinogen, serum albumin and WBC. Multivariate-adjusted analysis found a high concentration of CRP was significantly associated with obesity, but attenuated the association in other markers. In an analysis restricted to people aged 40-69 years, body fat levels were more strongly associated with CRP and fibrinogen than with BMI only. Furthermore, only CRP concentrations were significantly elevated according to weight gain. Strong associations of CRP concentration with BMI, body fat, and weight gain were found among elderly Japanese, but not with fibrinogen, serum albumin or WBC.
机译：由于肥胖被认为是通过低度慢性炎症在动脉粥样硬化中发挥关键作用，因此本研究旨在调查体重指数（BMI），体脂和体重增加与优化的炎症标志物在1,053名居民中的相关性。来自日本农村社区的40岁及以上（2000年总人口= 3,940）。报告患有感冒的人和未进行血液检查的人被排除在外。使用C反应蛋白（CRP），纤维蛋白原，血清白蛋白和白细胞（WBC）计数作为炎症指标，通过常规方法计算体内脂肪，并评估20岁以来的体重变化。随着CRP四分位数的增加，BMI和体脂显着增加，并且与BMI或体脂的相关系数较高。发现纤维蛋白原，血清白蛋白和白细胞有相似的关联。多变量校正后的分析发现，高浓度的CRP与肥胖显着相关，但减弱了其他指标的相关性。在一项针对年龄在40-69岁之间的人群的分析中，与仅与BMI相比，CRP和纤维蛋白原与体内脂肪水平的相关性更高。此外，根据体重增加，仅CRP浓度显着升高。在日本老年人中，CRP浓度与BMI，身体脂肪和体重增加密切相关，而与纤维蛋白原，血清白蛋白或WBC无关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号