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Evaluating vitamin D status. Implications for preventing and managing osteoporosis and other chronic diseases.

机译:评估维生素D的状态。对预防和管理骨质疏松症和其他慢性疾病的意义。

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摘要

Recent studies have added new dimensions to the fund of knowledge on vitamin D. In addition to the classic role of vitamin D in preventing rickets and osteomalacia, a preventive effect against osteoporotic fractures has been convincingly established, and abundant evidence suggests a role in preventing malignancies and autoimmune diseases. Serum 25-OH-vitamin D assay is a simple test for evaluating vitamin D status. However, recent review articles indicate that current reference ranges for serum 25-OH-vitamin D are too low. An appropriate lower normal limit may be between 50-100 nmol/l (20-40 ng/ml). Standard supplement dosages may fail to provide concentrations above this range.
机译:最近的研究为维生素D知识的基础增加了新的维度。除了维生素D在预防病和骨软化症中的经典作用外,已经令人信服地确立了对骨质疏松性骨折的预防作用,并且大量证据表明该作用在预防恶性肿瘤中具有作用和自身免疫性疾病。血清25-OH-维生素D测定是评估维生素D状态的简单测试。但是,最近的评论文章指出,目前血清25-OH-维生素D的参考范围太低。适当的正常下限可能在50-100 nmol / l(20-40 ng / ml)之间。标准补充剂量可能无法提供高于该范围的浓度。

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