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首页> 外文期刊>Circulation journal >Longitudinal risk of cardiovascular events in relation to depression symptoms after discharge among survivors of myocardial infarction. Osaka Acute Coronary Insufficiency Study.
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Longitudinal risk of cardiovascular events in relation to depression symptoms after discharge among survivors of myocardial infarction. Osaka Acute Coronary Insufficiency Study.

机译：心肌梗死幸存者出院后与抑郁症状相关的心血管事件的纵向风险。大阪急性冠状动脉供血不足研究。

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摘要

BACKGROUND: The purpose of this study was to investigate the association between depression symptoms 1 year after onset and subsequent cardiovascular events among survivors of myocardial infarction (MI). METHODS AND RESULTS: The participants were recruited from respondents to a district-based survey known as the Osaka Acute Coronary Insufficiency Study. Of 4,271 eligible MI patients, 1,951 completed the Zung Self-Rating Depression Scale (SDS) at their 1-year follow-up examination. After excluding patients who experienced cardiovascular events within 1 year, the data for the remaining 1,307 male patients and 280 female patients were analyzed. Among male patients, depression status at 1 year after onset of MI was significantly related to risk of subsequent cardiovascular events throughout the follow-up period (median 2.9 years). The male patients in the top vs. bottom tertiles of SDS scores (top tertile being >/=42) had a multivariable-adjusted hazard ratio (HR) of 1.67 (95% confidence interval (CI) 1.01-2.77, P=0.04), and a 1-SD increment in SDS score was significantly related to a heightened risk of cardiovascular events, with a multivariable-adjusted HR of 1.30 (95%CI 1.07-1.58, P=0.01). There were no significant associations between SDS scores and cardiovascular events among female patients. CONCLUSIONS: Depression symptoms 1 year after onset of MI are a significant predictor of subsequent cardiovascular events for male patients.
机译：背景：这项研究的目的是调查心肌梗塞（MI）幸存者发病1年后抑郁症状与随后发生的心血管事件之间的关系。方法和结果：参与者是从受访者中招募来的，该调查基于地区性调查，称为大阪急性冠状动脉供血不足研究。在4,271名合格的MI患者中，有1951名在他们的1年随访检查中完成了Zung自评抑郁量表（SDS）。在排除一年内​​发生心血管事件的患者后，分析了其余1307名男性患者和280名女性患者的数据。在男性患者中，MI发生1年后的抑郁状态与整个随访期间（中位2.9年）随后发生心血管事件的风险显着相关。 SDS得分最高与最低三分位数的男性患者（最高三分位数> / = 42）具有1.67的多变量调整后的危险比（HR）（95％置信区间（CI）1.01-2.77，P = 0.04） ，而SDS得分的1-SD升高与心血管事件的风险增加显着相关，多变量调整后的HR为1.30（95％CI 1.07-1.58，P = 0.01）。女性患者的SDS评分与心血管事件之间无显着相关性。结论：MI发作1年后的抑郁症状是男性患者随后发生心血管事件的重要预测指标。

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