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首页> 外文期刊>JAMA pediatrics >Beneficial or neutral effect of breastfeeding on cognitive outcomes in children of mothers with epilepsy?
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Beneficial or neutral effect of breastfeeding on cognitive outcomes in children of mothers with epilepsy?

机译：母乳喂养对癫痫母亲的孩子的认知结局有有益或中性的作用？

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While these known factors remained associated with the IQ outcomes, breastfeeding was also associated: breastfed children had a mean IQ 4 points higher than that of non-breastfed children, with a mean difference of 12 IQ points for the valproate sodium-exposed group (IQ of 94 for 25 children not breastfed compared with 106 for 11 children breastfed). These results must be couched in their research context, which is that 181 children were included for analysis because both breastfeeding and IQ data were available only on these, a subset of 311 births in the intent-to-treat sample (58%). However, an analysis of the sensitivity of the results to missing data showed that missing data could not explain the findings. The mean duration of breastfeeding was 7.2 months overall, and the proportion of breastfed children was similar in each nonrandomized maternal epilepsy treatment group of valproate, carbamazepine, phenytoin, or lamotrigine at 31% to 49%.
机译：尽管这些已知因素仍与智商结果相关，但母乳喂养也有关联：母乳喂养的孩子的平均智商比非母乳喂养的孩子高4点，丙戊酸钠暴露组的平均智商差为12点。 25例未进行母乳喂养的儿童为94例，而11例进行母乳喂养的儿童为106例）。这些结果必须在他们的研究背景下考虑，即包括181个孩子进行分析，因为仅母乳喂养和IQ数据都可用于这些孩子，意向性治疗样本中有311个婴儿的子集（58％）。但是，对结果对缺失数据的敏感性的分析表明，缺失数据无法解释发现。总体平均母乳喂养时间为7.2个月，丙戊酸，卡马西平，苯妥英或拉莫三嗪的每个非随机孕产妇癫痫治疗组中，母乳喂养儿童的比例相似。

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