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首页> 外文期刊>JAMA otolaryngology-- head & neck surgery >Use of vascularized muscle flaps in the healing of compromised wounds
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Use of vascularized muscle flaps in the healing of compromised wounds

机译：使用血管化的肌皮瓣修复受损的伤口

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As described in other studies, the authors found that the use of nonirradiated, vascularized tissue reduced the incidence and duration of fistula. Interestingly, Patel et al1 found that the pectoralis myofascial flap, when applied as an overlay flap, was the most efficacious technique to reduce the rate of postoperative fistula. This study represents an important contribution to the literature because the rates of salvage surgery and the attendant complications associated with those surgical procedures has risen significantly over the past 2 decades. While there have been several small series evaluating the techniques for pharyngotomy closure, this multi-institutional retrospective analysis highlights the importance of using vascularized muscle for healing a compromised wound bed. There is scientific evidence to suggest that muscle improves healing, compared with fasciocutane-ous tissue.2 This article provides important insight into the healing of compromised wounds and suggests that vascularized muscle flaps, like omentum,3 provide a benefitfor the closure of radiation-compromised pharyngotomy defects. This work also raises questions related to the mechanism of action of healing, as well as the question whether muscles secrete factors that promote healing, as has been demonstrated in omental flaps.
机译：如其他研究所述，作者发现使用未辐照的血管化组织可减少瘘管的发生率和持续时间。有趣的是，Patel等[1]发现，胸膜肌筋膜瓣作为覆盖瓣应用时，是降低术后瘘管发生率的最有效技术。这项研究代表了文献方面的重要贡献，因为在过去的20年中，抢救手术的速度以及与这些手术相关的并发症。虽然有几个小系列评估咽喉切开术的技术，但这种多机构的回顾性分析强调了使用血管化肌肉修复受损伤口床的重要性。有科学证据表明，与筋膜组织相比，肌肉可以改善愈合。2本文提供了对受损伤口愈合的重要见解，并建议血管化的皮瓣，如网膜，3对于关闭放射线受损的患者有好处。咽部切开术的缺陷。这项工作还提出了有关愈合作用机制的问题，以及肌肉是否分泌促进愈合的因子的问题，正如在网膜皮瓣中所证实的那样。

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