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首页> 外文期刊>JAMA psychiatry >State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder
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State-Dependent Differences in Emotion Regulation Between Unmedicated Bipolar Disorder and Major Depressive Disorder

机译:非药物性双相情感障碍和重度抑郁症的情绪调节状态相关差异

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IMPORTANCE Major depressive disorder (MDD) and bipolar disorder (BD) are difficult to distinguish clinically during the depressed or remitted states. Both mood disorders are characterized by emotion regulation disturbances; however, little is known about emotion regulation differences between MDD and BD. Better insight into these differences would be helpful for differentiation based on disorder-specific underlying pathophysiological mechanisms. Previous studies comparing these disorders often allowed medication use, limiting generalizability and validity. Moreover, patients with MDD and BD were mostly compared during the depressed, but not the remitted, state, while state might potentially modulate differences between MDD and BD.
机译:重要事项在抑郁或缓解状态期间,很难在临床上区分重度抑郁症(MDD)和双相情感障碍(BD)。两种情绪障碍均以情绪调节障碍为特征。然而,关于MDD和BD之间的情绪调节差异知之甚少。更好地了解这些差异将有助于基于特定于疾病的潜在病理生理机制进行区分。以前比较这些疾病的研究通常允许药物治疗,从而限制了推广性和有效性。此外,在抑郁状态下,大多数是比较MDD和BD患者,而在缓解状态下则没有,而状态可能会调节MDD和BD之间的差异。

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