首页> 外文期刊>Journal of affective disorders >Sleep functioning in relation to mood, function, and quality of life at entry to the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
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Sleep functioning in relation to mood, function, and quality of life at entry to the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).

机译:进入双相情感障碍系统治疗增强计划(STEP-BD)时,与情绪,功能和生活质量相关的睡眠功能。

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BACKGROUND: Sleep disturbance in bipolar disorder can be both a risk factor and symptom of mood episodes. However, the associations among sleep and clinical characteristics, function, and quality of life in bipolar disorder have not been fully investigated. METHODS: The prevalence of sleep disturbance, duration, and variability, as well as their associations with mood, function, and quality of life, was determined from 2024 bipolar patients enrolled in the National Institute of Mental Health Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD). RESULTS: Analyses indicated that 32% of patients were classified as short sleepers, 38% normal sleepers, and 23% long sleepers. Overall, short sleepers demonstrated greater mood elevation, earlier age at onset, and longer illness duration compared to both normal and long sleepers. Both short and long sleepers had greater depressive symptoms, poorer life functioning, and quality of life compared to normal sleepers. DISCUSSION: Short sleep duration in bipolar disorder was associated with a more severe symptom presentation, whereas both short and long sleep duration are associated with poorer function and quality of life compared to normal sleep duration. Sleep disturbance could be a trait marker of bipolar disorder, though longitudinal assessments are warranted to assess potential causal relations and the longer-term implications of sleep disturbance in bipolar disorder.
机译:背景:双相情感障碍的睡眠障碍可能是情绪发作的危险因素和症状。但是,尚未完全研究双相情感障碍的睡眠与临床特征,功能和生活质量之间的关联。方法:从2024名参加美国国家精神卫生系统性双相情感障碍疾病系统治疗增强计划的双相情感障碍患者( STEP-BD)。结果:分析表明,有32%的患者被归类为短睡眠者,38%的正常睡眠者和23%的长睡眠者。总体而言,与正常和长时间睡眠者相比,睡眠时间短的人表现出更高的情绪提升,发病年龄更早,病程更长。与正常的睡眠者相比,短期和长期睡眠者都具有更大的抑郁症状,较差的生活功能和生活质量。讨论:双相情感障碍的短暂睡眠时间与更严重的症状表现有关,而与正常睡眠时间相比,短期和长期睡眠都与较差的功能和生活质量有关。睡眠障碍可能是双相情感障碍的特征标记,尽管纵向评估有必要评估双相情感障碍的潜在因果关系和长期睡眠影响。

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