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Synthesis of quantitative and qualitative research: an example using Critical Interpretive Synthesis

机译:定量和定性研究的综合:以临界解释综合为例

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Synthesis of quantitative and qualitative research: an example using Critical Interpretive Synthesis. Aim. This paper is a report of a Critical Interpretive Synthesis to synthesize quantitative research, in the form of an effectiveness review and a guideline, with qualitative research to examine the use of morphine to treat cancer-related pain. Background. Critical Interpretive Synthesis is a new method of reviewing, developed from meta-ethnography, which integrates systematic review methodology with a qualitative tradition of enquiry. It has not previously been used specifically to synthesize effectiveness and qualitative literature. Data sources. An existing systematic review of quantitative research and a guideline examining the effectiveness of oral morphine to treat cancer pain were identified. Electronic searches of Medline, CINAHL, Embase, PsychINFO, Health Management Information Consortium database and the Social Science Citation Index to identify qualitative research were carried out in May 2008. Review methods. Qualitative research papers reporting on the use of morphine to treat cancer pain were identified. The findings of the effectiveness research were used as a framework to guide the translation of findings from qualitative research using an integrative grid. A secondary translation of findings from the qualitative research, not specifically mapped to the effectiveness literature, was guided by the framework. Results. Nineteen qualitative papers were synthesized with the quantitative effectiveness literature, producing 14 synthetic constructs. These were developed into four synthesizing arguments which drew on patients', carers' and healthcare professionals' interpretations of the meaning and context of the use of morphine to treat cancer pain. Conclusion. Critical Interpretive Synthesis can be adapted to synthesize reviews of quantitative research into effectiveness with qualitative research and fits into an existing typology of approaches to synthesizing qualitative and quantitative research.
机译:定量和定性研究的综合:使用关键解释综合的例子。目标。本文是《关键解释性综合》的一项报告,以有效性审查和指南的形式综合了定量研究,并进行了定性研究,以研究吗啡在治疗癌症相关疼痛方面的应用。背景。批判性解释综合是一种从元种族志学发展起来的新评论方法,该方法将系统的评论方法与定性的询问传统相结合。以前尚未专门使用它来合成有效性和定性文献。数据源。确定了现有的定量研究的系统综述和检查口服吗啡治疗癌症疼痛的有效性的指南。 2008年5月对Medline,CINAHL,Embase,PsychINFO,健康管理信息联盟数据库和社会科学引文索引进行了电子检索,以进行定性研究。审查方法。鉴定出了有关使用吗啡治疗癌症疼痛的定性研究论文。有效性研究的结果被用作框架,以指导使用集成网格的定性研究结果的翻译。该框架指导了定性研究结果的二次翻译,但未专门针对有效性文献。结果。利用定量有效性文献合成了19篇定性论文,产生了14种合成构建体。这些被发展为四个综合论据,这些论据借鉴了患者,护理人员和医疗保健专业人员对使用吗啡治疗癌症疼痛的含义和上下文的解释。结论。批判性解释合成可用于将定量研究的评论与定性研究进行综合,并适合现有的定性和定量研究综合方法。

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