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首页> 外文期刊>Japanese journal of clinical oncology. >Health-related quality of life using SF-8 and EPIC questionnaires after treatment with radical retropubic prostatectomy and permanent prostate brachytherapy.
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Health-related quality of life using SF-8 and EPIC questionnaires after treatment with radical retropubic prostatectomy and permanent prostate brachytherapy.

机译:根治性耻骨后前列腺切除术和永久性前列腺近距离放射治疗后,使用SF-8和EPIC问卷调查与健康相关的生活质量。

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OBJECTIVE: The health-related quality of life (HRQOL) after treatment of prostate cancer is examined using a new HRQOL tool. HRQOL, based on the expanded prostate cancer index composite (EPIC) and SF-8 questionnaires, was prospectively compared after either a radical retropubic prostatectomy (RRP) or a permanent prostate brachytherapy (PPB) at a single institute. METHODS: Between October 2005 and June 2007, 96 patients were treated by an RRP and 88 patients were treated by a PPB. A HRQOL survey was completed at baseline, and at 1, 3, 6 and 12 months after treatment, prospectively. RESULTS: The general HRQOL in the RRP and PPB groups was not different after 3 months. However, at baseline and 1 month after treatment, the mental component summary was significantly better in the PPB group than in the RRP group. Moreover, the disease-specific HRQOL was worse regarding urinary and sexual functions in the RRP group. Urinary irritative/obstructive was worse in the PPB group, but urinary incontinence was worse in the RRP group and had not recovered to baseline after 12 months. The bowel function and bother were worse in the PPB group than in the RRP group after 3 months. In the RRP group, the patients with nerve sparing demonstrated the same scores in sexual function as the PPB group. CONCLUSIONS: This prospective study revealed the differences in the HRQOL after an RRP and PPB. Disease-specific HRQOL is clarified by using EPIC survey. These results will be helpful for making treatment decisions.
机译:目的:使用新的HRQOL工具检查前列腺癌治疗后与健康相关的生活质量(HRQOL)。根据扩展的前列腺癌指数综合指数(EPIC)和SF-8问卷对HRQOL进行了前瞻性比较,在单个机构进行了耻骨后前列腺癌根治术(RRP)或永久性前列腺近距离放疗(PPB)之后。方法:2005年10月至2007年6月,RRP治疗96例,PPB治疗88例。 HRQOL调查在基线以及治疗后的1、3、6和12个月前完成。结果:3个月后,RRP和PPB组的总体HRQOL无差异。然而,在基线和治疗后1个月,PPB组的心理成分总结明显好于RRP组。此外,在RRP组中,特定疾病的HRQOL在泌尿和性功能方面较差。 PPB组的尿道刺激性/阻塞性更严重,而RRP组的尿失禁则更严重,并且在12个月后未恢复到基线。 3个月后,PPB组的肠功能和打扰较RRP组差。在RRP组中,神经稀疏患者的性功能得分与PPB组相同。结论:这项前瞻性研究揭示了RRP和PPB后HRQOL的差异。通过使用EPIC调查来明确疾病特定的HRQOL。这些结果将有助于制定治疗方案。

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