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首页> 外文期刊>Journal of applied physiology >Four weeks of normobaric 'live high-train low' do not alter muscular or systemic capacity for maintaining pH and K + homeostasis during intense exercise
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Four weeks of normobaric 'live high-train low' do not alter muscular or systemic capacity for maintaining pH and K + homeostasis during intense exercise

机译：正常运动四个星期的常压“低强度生活”不会改变肌肉或全身在剧烈运动中维持pH和K +稳态的能力

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It was investigated if athletes subjected to 4 wk of living in normobaric hypoxia (3,000 m; 16 h/day) while training at 800-1,300 m ["live high-train low" (LHTL)] increase muscular and systemic capacity for maintaining pH and K + homeostasis as well as intense exercise performance. The design was double-blind and placebo controlled. Mean power during 30-s all-out cycling was similar before and immediately after LHTL (650 ± 31 vs. 628 ± 32 W; n = 10) and placebo exposure (658 ± 22 vs. 660 ± 23 W; n = 6). Supporting the performance data, arterial plasma pH, lactate, and K + during submaximal and maximal exercise were also unaffected by the intervention in both groups. In addition, muscle buffer capacity (in mmol H +·kg dry wt -1·pH -1) was similar before and after in both the LHTL (140 ± 12 vs. 140 ± 16) and placebo group (145 ± 2 vs. 140 ± 3). The expression of sarcolemmal H + transporters (Na +/H + exchanger 1, monocarboxylate transporters 1 and 4), as well as expression of Na +-K + pump subunits-α1, -α 2, and -β1 was also similar before and after the intervention. In conclusion, muscular and systemic capacity for maintaining pH and K + balance during exercise is similar before and after 4 wk of placebo-controlled normobaric LHTL. In accordance, 30-s all-out sprint ability was similar before and after LHTL.
机译：研究了在常压缺氧（3,000 m; 16 h / day）中经历4 wk的运动员，同时在800-1,300 m [“ live high-train low”（LHTL）]下训练是否增加了维持pH的肌肉和全身能力和K +动态平衡以及激烈的运动表现。该设计是双盲和安慰剂对照的。 LHTL之前和之后（650±31 vs. 628±32 W; n = 10）和安慰剂暴露（658±22 vs. 660±23 W; n = 6）前后，平均功率在30秒全周期循环中是相似的。支持性能数据的两组患者的干预也未影响次最大运动和最大运动期间的动脉血浆pH，乳酸和K +。此外，LHTL（140±12 vs. 140±16）和安慰剂组（145±2 vs. 145）前后的肌肉缓冲能力（以mmol H +·kg干wt -1·pH -1为单位）相似。 140±3）。肌膜H +转运蛋白（Na + / H +交换子1，单羧酸盐转运蛋白1和4）的表达以及Na + -K +泵亚基-α1，-α2和-β1的表达在之前和之前也相似。干预后。总之，在运动期间维持安慰剂对照的常压LHTL 4周前后，肌肉和全身维持pH和K +平衡的能力相似。因此，LHTL之前和之后的30秒全速冲刺能力相似。

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