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Flavin-grafted poly(vinyl alcohol): Preparation and properties

机译:黄素接枝的聚乙烯醇:制备与性能

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An NAD(P)H oxidase-like activity was found in semisynthetic flavoadducts, prepared from an aldehyde derivative of riboflavin and commercial poly(vinylalcohol) (PVA), previously grafted with aminopropyl side chains. Both water-soluble and water-insoluble beaded preparations were obtained. The products showed a noticeable NAD(P)H oxidase-like activity, converting the nucleotide substrate to its oxidized counterpart NAD(P)(+) at the expense of molecular oxygen, the latter being reduced to hydrogen peroxide. In contrast to some "true" beta-NAD(P)H oxidases, the PVA adducts do not require the presence of additional flavin adenine dinucleotide (FAD) to work; some properties of the flavoadducts were studied that make these flavoadducts good candidates for technological applications. (C) 2002 Wiley Periodicals, Inc. [References: 14]
机译:在半合成的黄酮加合物中发现了类似NAD(P)H氧化酶的活性,其由核黄素的醛衍生物和市售的聚乙烯醇(PVA)预先接枝了氨丙基侧链制成。获得水溶性和水不溶性珠粒制剂。产物显示出明显的NAD(P)H氧化酶样活性,以分子氧为代价将核苷酸底物转化为其氧化的对应物NAD(P)(+),而分子氧被还原为过氧化氢。与某些“真正的”β-NAD(P)H氧化酶相反,PVA加合物不需要额外的黄素腺嘌呤二核苷酸(FAD)即可起作用。研究了黄酮加合物的一些性质,使其成为技术应用的良好候选者。 (C)2002 Wiley Periodicals,Inc. [参考:14]

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