首页> 外文期刊>Journal of Applied Polymer Science >Polyether-segmented nylon hemodialysis membrane. V. Evaluation of blood compatibility of polyether-segmented nylons
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Polyether-segmented nylon hemodialysis membrane. V. Evaluation of blood compatibility of polyether-segmented nylons

机译:聚醚分段尼龙血液透析膜。五,聚醚分段尼龙的血液相容性评估

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摘要

The biocompatibility of poly(propylene oxide)-segmented nylon610 (PPO-Ny610), poly(ethylene oxide)-segmented nylon610 (PEO-Ny610), poly(ethylene oxide)-segmented nylonM10 (PEO-NyM10), and poly(ethylene oxide)-segmented nylon69/M10 (PEO-Ny69/M10) hollow fibers were investigated in terms of the transient leukopenia by the extracorporeal circulation in a rabbit. PPO-Ny610 and PEO-Ny610 hollow fibers showed that the minimum leukocyte counts during the circulations were >80% against the initial count of leukocyte. These results indicate that these polymers have good blood compatibility. In PEO-NyM10 and PEO-Ny69/M10, the remarkable decreases of the leukocyte count were observed and the minimum counts were in the range of 45-50%. From the evaluation results of homo nylons (Ny610 and NyM10) hollow fibers, the low blood compatibilities observed in PEO-NyM10 and PEO-Ny69/M10 are not attributed to the chemical structure of the nylon blocks. (C) 1998 John Wiley & Sons, Inc. [References: 11]
机译:聚环氧丙烷分段的尼龙610(PPO-Ny610),聚环氧乙烷分段的尼龙610(PEO-Ny610),聚环氧乙烷分段的尼龙M10(PEO-NyM10)和聚环氧乙烷的生物相容性通过兔体内的体外循环研究了瞬时节段性白细胞减少症对)片段尼龙69 / M10(PEO-Ny69 / M10)中空纤维的影响。 PPO-Ny610和PEO-Ny610中空纤维显示,在循环过程中最小白细胞计数相对于白细胞初始计数> 80%。这些结果表明这些聚合物具有良好的血液相容性。在PEO-NyM10和PEO-Ny69 / M10中,观察到白细胞计数显着下降,最小计数在45-50%的范围内。从均质尼龙(Ny610和NyM10)中空纤维的评估结果来看,在PEO-NyM10和PEO-Ny69 / M10中观察到的低血液相容性不归因于尼龙嵌段的化学结构。 (C)1998 John Wiley&Sons,Inc. [参考:11]

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