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首页> 外文期刊>Journal of applied toxicology >Hematological parameters in tench Tinca tinca after short term exposure to lead.
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Hematological parameters in tench Tinca tinca after short term exposure to lead.

机译：短期接触铅后，丁ten的血液学参数。

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摘要

Alterations in the hematological parameters of Tinca tinca were studied after exposure to lead at different concentrations and durations of exposure. Dose of 75/24 (ppm/h) did not cause significant change in any blood parameter. The 300/48 dose caused a significant increase in hematocrit (Hct), mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) and a significant decrease in red blood cell (RBC) count and mean corpuscular hemoglobin concentration (MCHC). The 30/24 dose caused a significant increase in Hct and RBC count only. The 30/96 dose caused a significant increase in Hct and a significant decrease in MCHC only. The 30/504 dose caused a significant decrease in RBC count and a significant increase in MCV and MCH. The 75/96 dose caused a significant increase in Hct and a significant decrease in MCH and MCHC. The 75/504 dose caused a significant decrease in Hct, hemoglobin (Hb) and RBC count, and a significant increase in MCV and MCH. These alterations were attributed to direct or feedback responses of structural damage to RBC membranes resulting in hemolysis and impairment in hemoglobin synthesis, stress related release of RBCs from the spleen and hypoxia, induced by exposure to lead.
机译：在暴露于不同浓度和暴露时间的铅后，研究了丁卡丁卡血液学参数的变化。 75/24（ppm / h）的剂量并未引起任何血液参数的显着变化。 300/48剂量引起血细胞比容（Hct），平均红细胞体积（MCV）和平均红细胞血红蛋白（MCH）的显着增加，以及红细胞（RBC）计数和平均红细胞血红蛋白浓度（MCHC）的显着降低。 30/24剂量仅导致Hct和RBC计数显着增加。 30/96剂量仅导致Hct显着增加，而MCHC则显着减少。 30/504剂量导致RBC计数显着减少，MCV和MCH显着增加。 75/96剂量导致Hct显着增加，MCH和MCHC显着下降。 75/504剂量导致Hct，血红蛋白（Hb）和RBC计数显着减少，MCV和MCH显着增加。这些改变归因于对红细胞膜结构性损伤的直接或反馈反应，导致溶血和血红蛋白合成受损，与铅相关的应激相关的红细胞从脾脏的释放和缺氧。

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