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首页> 外文期刊>Journal of applied toxicology >Detoxification of lantana hepatotoxin, lantadene A, using Alcaligenes faecalis.
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Detoxification of lantana hepatotoxin, lantadene A, using Alcaligenes faecalis.

机译:使用粪产碱菌对马tana丹肝毒素,兰丹烯A进行解毒。

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摘要

Detoxification of lantadene A (LA), the hepatotoxin from Lantana camara var. aculeata, by the bacterial strain Alcaligenes faecalis has been investigated. Lantadene A induced hepatotoxicity concomitant with increases in plasma bilirubin, blood plasma enzymes and histopathological lesions that typify lantana toxicity. The extract of fermentation broth in which LA was incubated with A. faecalis did not elicit any alterations in blood enzyme prolife or liver histopathology, which were comparable with the control group. It is concluded that A. faecalis detoxified LA and no noxious product was formed on incubation of LA with A. faecalis. Copyright 2001 John Wiley & Sons, Ltd.
机译:兰丹丹(Latana camara var)的肝毒素-兰丹烯A(LA)的解毒。通过细菌菌株粪便产碱杆菌对球菌进行了研究。兰丹烯A诱导的肝毒性伴随血浆胆红素,血浆酶和组织病理学损害的增加,代表了马tana丹的毒性。将LA与粪肠球菌一起培养的发酵液提取物未引起血液酶增殖或肝脏组织病理学的任何改变,这与对照组相当。结论是粪肠球菌对LA进行了排毒,并且在将LA与粪肠球菌一起孵育时没有形成有害产物。版权所有2001 John Wiley&Sons,Ltd.

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