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首页> 外文期刊>Journal of assisted reproduction and genetics >Expression of interleukin-22 in decidua of patients with early pregnancy and unexplained recurrent pregnancy loss
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Expression of interleukin-22 in decidua of patients with early pregnancy and unexplained recurrent pregnancy loss

机译:白细胞介素22在早孕和原因不明的反复性流产患者蜕膜中的表达

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摘要

Researchers have hypothesized that an imbalance of immune cells in the uterine decidua and a dysfunction in cytokines they produce may contribute to recurrent pregnancy loss (RPL). The objective of this study was to determine if IL-22, IL-23 and IL-17 are expressed abnormally in the decidua of patients with RPL compared to those women with a normal pregnancy. We also sought to confirm that uterine natural killer (uNK) cells are lower in the decidua of patients with RPL, as well as identify IL-22 expression by uNK cells.
机译:研究人员假设,子宫蜕膜中免疫细胞的失衡和它们产生的细胞因子功能障碍可能导致复发性流产(RPL)。这项研究的目的是确定与正常妊娠的女性相比,RPL患者的蜕膜中IL-22,IL-23和IL-17是否异常表达。我们还试图确认在RPL患者的蜕膜中子宫自然杀伤(uNK)细胞较低,并通过uNK细胞鉴定IL-22表达。

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