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首页> 外文期刊>Journal of atherosclerosis and thrombosis. >Risk factors for coronary heart disease in the Japanese--comparison of the background of patients with acute coronary syndrome in the ASPAC study with data obtained from the general population. Asia-Pacific Collaboration on CHD Risk Factor Interventi
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Risk factors for coronary heart disease in the Japanese--comparison of the background of patients with acute coronary syndrome in the ASPAC study with data obtained from the general population. Asia-Pacific Collaboration on CHD Risk Factor Interventi

机译:日本人冠心病的危险因素-比较ASPAC研究中急性冠脉综合征患者的背景和从普通人群中获得的数据。冠心病危险因素干预的亚太合作

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摘要

The relative importance of metabolic risk factors for coronary heart disease (CHD) in the Japanese is assessed by comparing their prevalence in patients with acute coronary syndrome (ACS) enrolled in the Asia-Pacific Collaboration on CHD Risk Factor Intervention (ASPAC) study to that obtained by a serum lipid survey carried out in 1990 and also by comparing them to the ASPAC data from other countries and regions in this area. Hypertension was the most prevalent risk factor among Japanese patients with ACS as in the other countries and regions. The prevalence of obesity with a body mass index (BMI) of 30 or more was several times higher than that in the general population, although the rate was still much lower than in New Zealand and Singapore. In addition to hypercholesterolemia, hypertriglyceridemia and diabetes mellitus were frequently found in Japanese patients with ACS. When the prevalence of metabolic risk factors was compared between people with and without hypertension in the general population, the most remarkable difference was seen in BMI, followed by triglyceride and total cholesterol. These results indicate that hypertriglyceridemia and diabetes mellitus may be more important CHD risk factors in the Japanese population than LDL-cholesterol.
机译:通过比较亚太地区冠心病危险因素干预研究(ASPAC)中参与研究的急性冠脉综合征(ACS)患者的患病率,比较日本人中冠心病(CHD)代谢危险因素的相对重要性。通过1990年进行的血清脂质调查并与该地区其他国家和地区的ASPAC数据进行比较,获得了这些数据。与其他国家和地区一样,高血压是日本ACS患者中最普遍的危险因素。体重指数(BMI)为30或更高的肥胖患病率比普通人群高出几倍,尽管这一比例仍远低于新西兰和新加坡。除高胆固醇血症外,日本ACS患者还经常发现高甘油三酯血症和糖尿病。当比较一般人群中有高血压和无高血压的人群中代谢危险因素的患病率时,最显着的差异是BMI,其次是甘油三酸酯和总胆固醇。这些结果表明,在日本人群中,高甘油三酯血症和糖尿病可能是比LDL-胆固醇更重要的CHD危险因素。

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