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首页> 外文期刊>Journal of biological inorganic chemistry: JBIC: a publication of the Society of Biological Inorganic Chemistry >Metals in medicine: metal-related diseases-Synthesis and preliminary biological investigation of novel NHC gold(I) complexes as potential anticancer agents
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Metals in medicine: metal-related diseases-Synthesis and preliminary biological investigation of novel NHC gold(I) complexes as potential anticancer agents

机译：药物中的金属：与金属有关的疾病-作为潜在抗癌剂的新型NHC金（I）配合物的合成和初步生物学研究

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摘要

Platinum complexes are widely used in cancer treatment. However, the use of these drugs is limited by severe side effects and the development of resistance during the therapy. Therefore, new metal centers have been investigated to replace platinum. Among these metals, gold has raised particular interest and several complexes of gold(I) and (III) have been synthetized and tested against tumor cells [1].
机译：铂配合物广泛用于癌症治疗。但是，这些药物的使用受到严重的副作用和治疗过程中耐药性的发展的限制。因此，已经研究了新的金属中心来代替铂。在这些金属中，金引起了特别的兴趣，并且已经合成了几种金（I）和（III）配合物并针对肿瘤细胞进行了测试[1]。

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