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首页> 外文期刊>The journal of asthma >Clinical features cannot distinguish allergic from non-allergic asthma in children
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Clinical features cannot distinguish allergic from non-allergic asthma in children

机译：儿童的临床特征无法区分过敏性哮喘和非过敏性哮喘

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Objective. Environmental allergens are a major trigger of asthma, but not all asthmatics are allergic. This study was designed to review clinical characteristics in children with allergic and non-allergic asthma, based on responsiveness to allergy skin tests, in order to identify a combination of features that could distinguish allergic from non-allergic asthma in children. Methods. Medical records of 321 children who had allergy skin testing were reviewed, and demographic and clinical data were compared between allergic and non-allergic patients. Results. Approximately two-thirds of the asthmatic children had at least one positive skin test. These allergic patients were more likely to have a history of eczema or Medicaid insurance, but these findings had poor predictive value. There was no difference between allergic patients and non-allergic patients in terms of family history of atopy or asthma, home tobacco smoke exposure, age of onset of asthma, gender, rate of obesity, or asthma severity. Among the allergic asthma patients, neither the number of positive skin tests nor specific individual allergic sensitivities correlated with age of onset of asthma or asthma severity. Conclusions. This study failed to identify any combination of features that could reliably distinguish allergic from non-allergic asthma in children. Thus, all children with asthma should undergo allergy testing in order to identify potential allergic triggers in allergic patients and to avoid the institution of unnecessary environmental control measures in non-allergic patients.
机译：目的。环境过敏原是哮喘的主要诱因，但并非所有哮喘患者都过敏。这项研究旨在根据对过敏性皮肤测试的反应性来回顾过敏性和非过敏性哮喘儿童的临床特征，以便确定可以区分儿童过敏性和非过敏性哮喘的多种特征。方法。回顾了321名接受过敏皮肤测试的儿童的病历，并比较了过敏和非过敏患者的人口统计学和临床​​数据。结果。大约三分之二的哮喘儿童皮肤测试至少为阳性。这些变态反应患者更有可能患有湿疹或医疗补助保险史，但这些发现具有较差的预测价值。在过敏性或哮喘的家族病史，家庭吸烟暴露，哮喘发作的年龄，性别，肥胖率或哮喘严重程度方面，过敏患者和非过敏患者之间没有差异。在过敏性哮喘患者中，阳性皮肤试验的数量或特定的个人过敏敏感性均与哮喘发作年龄或哮喘严重程度无关。结论。这项研究未能确定可以可靠地区分儿童过敏性哮喘和非过敏性哮喘的特征的任何组合。因此，所有哮喘儿童都应进行过敏测试，以识别过敏患者中潜在的过敏触发因素，并避免对非过敏患者采取不必要的环境控制措施。

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