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Occupation and COPD: A brief review

机译:职业与COPD:简要回顾

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Background and aims. This review summarizes the scientific literature relevant to occupational risk factors for chronic obstructive pulmonary disease (COPD). Material and methods. This review emphasizes recent work in the field, while placing this in the context of two previous systematic reviews of the subject. Results. Both the earlier summaries of the literature estimated that the population attributable risk percent (PAR%) of COPD linked to occupational exposures is approximately 15%. More recent studies also strongly support the association between workplace exposures and COPD. Among never smokers, the PAR% for work-related factors may approach 40%. Emerging data also indicate that occupational exposures, at a minimum, are additive to smoking-associated risk of COPD. Conclusions. The PAR% for work-related COPD is at least 15%. Scientific significance. The consistency, strength, and plausibility of these data support a causal relationship between occupational exposures and COPD.
机译:背景和目标。这篇综述总结了与慢性阻塞性肺疾病(COPD)职业危险因素有关的科学文献。材料与方法。这篇综述着重介绍了该领域的最新工作,同时将其放在之前对该主题的两次系统评价的背景下。结果。文献的两个较早的摘要都估计,与职业接触有关的COPD人群可归因风险百分比(PAR%)约为15%。最近的研究也强烈支持工作场所暴露与COPD之间的关联。在从不吸烟者中,与工作有关的因素的PAR%可能接近40%。新兴数据还表明,职业接触至少是与吸烟相关的COPD风险的加成。结论。与工作相关的COPD的PAR%至少为15%。具有科学意义。这些数据的一致性,强度和合理性支持了职业暴露与COPD之间的因果关系。

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