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首页> 外文期刊>Journal of Biomechanics >Increased iris-lens contact following spontaneous blinking: Mathematical modeling
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Increased iris-lens contact following spontaneous blinking: Mathematical modeling

机译：自发眨眼后虹膜镜片接触增加：数学模型

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The purpose of this work was to study in silico how iris root rotation due to spontaneous blinking alters the iris contour. An axisymmetric finite-element model of the anterior segment was developed that included changes in the iris contour and the aqueous humor flow. The model geometry was based on average values of ocular dimensions. Blinking was modeled by rotating the iris root posteriorly and returning it back to the anterior. Simulations with maximum rotations of 2°, 4°, 6°, and 8° were performed. The iris-lens contact distance and the pressure difference between the posterior and anterior chambers were calculated. When the peak iris root rotation was 2°, the maximum iris-lens contact increased gradually from 0.28 to 0.34. mm within eight blinks. When the iris root was rotated by 6° and 8°, the pressure difference between the posterior and anterior chambers dropped from a positive value (1.23. Pa) to negative values (-0.86 and -1.93. Pa) indicating the presence of reverse pupillary block. Apparent iris-lens contact increased with steady blinking, and the increase became more pronounced as posterior rotation increased. We conclude that repeated iris root rotation caused by blinking could maintain the iris in a posterior position under normal circumstances, which would then lead to the clinically observed anterior drift of the iris when blinking is prevented.
机译：这项工作的目的是在计算机上研究自发眨眼引起的虹膜根部旋转如何改变虹膜轮廓。建立了前节的轴对称有限元模型，该模型包括虹膜轮廓和房水流动的变化。模型的几何形状基于眼图尺寸的平均值。通过向后旋转虹膜根并将其返回到前部来模拟眨眼。进行了最大旋转2°，4°，6°和8°的模拟。计算虹膜透镜的接触距离和前后房之间的压力差。当虹膜根旋转峰值为2°时，最大虹膜与镜片的接触度从0.28逐渐增加至0.34。 mm在八次眨眼内。当虹膜根旋转6°和8°时，后房和前房之间的压差从正值（1.23。Pa）下降到负值（-0.86和-1.93。Pa），表明存在反向瞳孔块。随着稳定的眨眼，虹膜镜片的表观接触增加，并且随着后旋转的增加，这种增加变得更加明显。我们得出的结论是，眨眼引起的虹膜根部反复旋转可以在正常情况下将虹膜保持在后部位置，当防止眨眼时，这将导致临床观察到的虹膜前移。

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