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首页> 外文期刊>Journal of Biomechanics >Nasal airway responses to nasal continuous positive airway pressure breathing: An in-vivo pilot study
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Nasal airway responses to nasal continuous positive airway pressure breathing: An in-vivo pilot study

机译：鼻气道对持续不断的气道正压呼吸的反应：一项体内试验研究

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摘要

The nasal cycle, through variation in nasal airflow partitioning, allows the upper airway to accommodate the contrasting demands of air conditioning and removal of entrapped air contaminants. The purpose of this study was to investigate the influence of nasal continuous positive airway pressure (nCPAP) breathing has on both nasal airflow partitioning and nasal geometry. Using a custom-made nasal mask, twenty healthy participants had the airflow in each naris measured during normal nasal breathing followed by nCPAP breathing. Eight participants also underwent magnetic resonance imaging (MRI) of the nasal region during spontaneous nasal breathing, and then nCPAP breathing over a range of air pressures. During nCPAP breathing, a simultaneous reduction in airflow through the patent airway together with a corresponding increase in airway flow within the congested nasal airway were observed in sixteen of the twenty participants. Nasal airflow resistance is inversely proportional to airway cross-sectional area. MRI data analysis during nCPAP breathing confirmed airway cross-sectional area reduced along the patent airway while the congested airway experienced an increase in this parameter. During awake breathing, nCPAP disturbs the normal inter-nasal airflow partitioning. This could partially explain the adverse nasal drying symptoms frequently reported by many users of this therapy. (C) 2016 Elsevier Ltd. All rights reserved.
机译：通过改变鼻气流分配的鼻循环，上呼吸道可以适应空调的不同需求和去除夹带的空气污染物。这项研究的目的是调查鼻持续呼吸道正压通气（nCPAP）对鼻气流分配和鼻腔几何形状的影响。使用定制的鼻罩，二十名健康参与者在正常鼻呼吸和nCPAP呼吸期间测量了每个鼻孔的气流。八名参与者在自发性鼻呼吸期间还对鼻区域进行了磁共振成像（MRI），然后在一定气压范围内进行了nCPAP呼吸。在nCPAP呼吸期间，在20名参与者中，有16名观察到同时流经专利气道的气流减少以及相应的鼻塞气道气流增加。鼻气流阻力与气道横截面积成反比。 nCPAP呼吸期间的MRI数据分析证实，沿呼吸道的横截面面积沿专利气道减小，而充血气道的该参数增大。在清醒呼吸期间，nCPAP干扰了正常的鼻内气流分配。这可以部分解释这种疗法的许多使用者经常报告的不良的鼻干症状。 （C）2016 Elsevier Ltd.保留所有权利。

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