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首页> 外文期刊>Journal of Biomechanics >FINITE ELEMENT STRESS ANALYSIS OF LEFT VENTRICULAR MECHANICS IN THE BEATING DOG HEART
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FINITE ELEMENT STRESS ANALYSIS OF LEFT VENTRICULAR MECHANICS IN THE BEATING DOG HEART

机译：狗心左心室力学的有限元应力分析。

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A three-dimensional finite element model was used to explore whether or not transmural distributions of end-diastolic and end-systolic fiber stress are uniform from the apex to the base of the canine left ventricular wall. An elastance model for active fiber stress was incorporated in an axisymmetric model that accurately represented the geometry and fiber angle distribution of the anterior free wall. The nonlinear constitutive equation for the resting myocardium was transversely isotropic with respect to the local fiber axis. Transmural distributions of end-diastolic fiber stress became increasingly nonuniform from midventricle toward the apex or the base. At a typical diastolic left ventricular pressure (1 kPa), the differences between largest and smallest fiber stresses were only 0.5 kPa near midventricle, compared with 4.6 kPa at the apex, and 3.3 kPa at the base. Transmural fiber stress differences at end-systole (14 kPa) were relatively small in regions from the base to the midventricle (13-22 kPa), but were larger between midventricle and the apex (30-43 kPa). All six three-dimensional end-diastolic strain components were within or very close to one standard deviation of published measurements through the midanterior left ventricular free wall of the passive canine heart [Omens et al., Am. J. Physiol. 261, H918-H928 (1991)]. End-systolic in-plane normal and shear strains also agreed closely with published experimental measurements in the beating dog heart [Waldman et al., Circ. Res. 63, 550-562 (1988)]. The results indicate that, unlike in the midventricle region that has been studied most fully, there may be significant regional nonhomogeneity of fiber stress in the normal left ventricle associated with regional variations in shape and fiber angle. [References: 37]
机译：使用三维有限元模型探讨舒张末期和收缩末期纤维应力的透壁分布从犬左心室壁的根尖到根部是否均匀。主动纤维应力的弹性模型被并入轴对称模型中，该模型精确地表示了前游离壁的几何形状和纤维角度分布。静止心肌的非线性本构方程相对于局部纤维轴是横向各向同性的。舒张末期纤维应力的透壁分布从心室向心尖或根部变得越来越不均匀。在典型的舒张期左心室压力（1 kPa）下，最大和最小纤维应力之间的差异仅在心室中部附近为0.5 kPa，而在心尖处为4.6 kPa，在基部为3.3 kPa。收缩期末的跨壁纤维应力差异（14 kPa）在从基部到心室的区域（13-22 kPa）相对较小，但在心室和心尖之间的跨膜纤维应力差异较大（30-43 kPa）。所有六个三维舒张末期应变分量均在被动犬心脏的左前中部左心室游离壁范围内，在已公布的测量值之内或非常接近[Omens et al。，Am。 J.生理学。 261，H918-H928（1991）]。收缩末期的平面法向应变和剪切应变也与在跳动的狗心脏中发表的实验测量结果非常吻合[Waldman等，Circ。 Res。 63，550-562（1988）]。结果表明，与在脑室中部区域进行的研究不同，在正常左心室中纤维应力可能存在明显的区域非均匀性，这与形状和纤维角度的区域变化有关。 [参考：37]

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