...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Biomechanics >New insight into deformation-dependent hydraulic permeability of gels and cartilage, and dynamic behavior of agarose gels in confined compression.
【24h】

New insight into deformation-dependent hydraulic permeability of gels and cartilage, and dynamic behavior of agarose gels in confined compression.

机译：对凝胶和软骨变形相关的水力渗透性以及封闭压缩中琼脂糖凝胶动力学行为的新见解。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Equilibrium, creep, and dynamic behaviors of agarose gels (2.0-14.8%) in confined compression were investigated in this study. The hydraulic permeabilities of gels were determined by curve-fitting creep data to the biphasic model (J. Biomech. Eng. 102 (1980) 73) and found to be similar in value to those published in the literature (AIChE J. 42 (1996) 1220). A new relationship between intrinsic permeability and volume fraction of water was found for agarose gel, capable of predicting deformation-dependent permeabilities of bovine articular cartilage and 2% agarose gel published in literature. This relationship is accurate for gels and cartilage over a wide range of permeabilities (four orders of magnitude variation). The dynamic stiffness of the gels increases with gel concentration and loading frequency (0.01-1.0Hz). The increase in dynamic stiffness with loading frequency is less pronounced for gels with higher concentrations. The results of this study provide a new insight into deformation-dependent permeability behavior of agarose gel and cartilage, and are important for understanding biological responses of cells to interstitial fluid flow in gel or in cartilage under dynamic mechanical loading.
机译：在这项研究中，研究了琼脂糖凝胶（2.0-14.8％）在压缩状态下的平衡，蠕变和动力学行为。凝胶的水力渗透率是通过将蠕变数据曲线拟合到双相模型来确定的（J. Biomech。Eng。102（1980）73），其值与文献中发表的值相似（AIChE J.42（1996） ）1220）。在琼脂糖凝胶中发现了固有渗透率与水体积分数之间的新关系，该关系能够预测牛关节软骨和2％琼脂糖凝胶的变形依赖性渗透率。这种关系对于各种渗透率（四个数量级变化）的凝胶和软骨都是准确的。凝胶的动态刚度随凝胶浓度和加载频率（0.01-1.0Hz）而增加。对于较高浓度的凝胶，动态刚度随加载频率的增加不太明显。这项研究的结果为琼脂糖凝胶和软骨的变形依赖性渗透性行为提供了新的见识，对于了解细胞对凝胶或软骨在动态机械载荷下细胞间质液流动的生物学反应具有重要意义。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号