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首页> 外文期刊>Journal of Biomechanics >Frictional properties of regenerated cartilage in vitro.
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Frictional properties of regenerated cartilage in vitro.

机译：体外再生软骨的摩擦特性。

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摘要

Although tribological function is the most important mechanical property of articular cartilage, few studies have examined this function in tissue-engineered cartilage. We investigated changes in the frictional properties of cartilage regenerated from the inoculation of rabbit chondrocytes into fibroin sponge. A reciprocating friction-testing apparatus was used to measure the friction coefficient of the regenerated cartilage under a small load. The specimen was slid against a stainless steel plate in a water vessel filled with physiological saline. The applied load was 0.03 N, the stroke length was 20 mm, and the mean sliding velocity was 0.8 mm/s. The friction coefficient of the regenerated cartilage decreased with increasing cultivation time, because a hydrophilic layer of synthesized extracellular matrix was formed on the fibroin sponge surface. The friction coefficient of the regenerated cartilage was as low as that of natural cartilage in the early stages of the sliding tests, but it increased with increasing duration of sliding owing to exudation of interstitial water from the surface layer.
机译：尽管摩擦学功能是关节软骨最重要的机械性能，但很少有研究检查组织工程软骨中的这种功能。我们研究了将兔软骨细胞接种到纤维蛋白海绵中后再生的软骨摩擦特性的变化。使用往复式摩擦测试仪测量小负荷下再生软骨的摩擦系数。将样品在装有生理盐水的水容器中靠在不锈钢板上滑动。施加的载荷为0.03 N，行程长度为20 mm，平均滑动速度为0.8 mm / s。再生软骨的摩擦系数随着培养时间的增加而降低，这是因为在纤维蛋白海绵表面形成了合成的细胞外基质的亲水层。在滑动试验的早期阶段，再生软骨的摩擦系数与天然软骨一样低，但是由于从表层渗出的间隙水，其随着滑动持续时间的增加而增加。

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