Numerical simulation of cardiovascular dynamics with healthy and diseased heart valves.

Korakianitis T; Shi Y

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Numerical simulation of cardiovascular dynamics with healthy and diseased heart valves.

机译：健康和患病心脏瓣膜的心血管动力学数值模拟。

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This paper presents a new concentrated parameter model for cardiovascular dynamics that includes an innovative model of heart valve dynamics, which is embedded in the overall model of the four chambers of the heart and the systemic and pulmonary circulation loops. The heart chambers are described with a variable elastance model, and the systemic and pulmonary loops are described with modified Windkessel models. In modelling the heart valve dynamics, the various factors that influence the valve motion are examined, and the governing differential equation for valve motion is derived. The heart valve model includes the influence of the blood pressure effect, the friction effect from the tissue, and from blood motion. As improvement from previous works, the contribution of the blood vortex effect in the vicinity of the valve leaflets to valve motion is specially considered. The proposed model is then used in simulation of healthy and certain pathological conditions such as mitral valve stenosis and aortic regurgitation. The predicted results agree well with results illustrated in cardiology textbooks.

机译：本文介绍了一种新的心血管动力学集中参数模型，其中包括一个创新的心脏瓣膜动力学模型，该模型嵌入了心脏四个腔以及全身和肺循环回路的整体模型中。用可变弹性模型描述心室，用改良的Windkessel模型描述全身和肺循环。在对心脏瓣膜动力学建模时，检查了影响瓣膜运动的各种因素，并推导了瓣膜运动的控制微分方程。心脏瓣膜模型包括血压影响，组织摩擦和血液运动的影响。作为对先前工作的改进，特别考虑了瓣膜小叶附近的血液涡旋效应对瓣膜运动的影响。然后将提出的模型用于模拟健康和某些病理状况，例如二尖瓣狭窄和主动脉瓣关闭不全。预测结果与心脏病学教科书中说明的结果非常吻合。

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《Journal of Biomechanics》 |2006年第11期|共19页
作者
Korakianitis T; Shi Y;
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正文语种 eng
中图分类生物工程学（生物技术）;
关键词
Models; heart valve effects; Motion; simulation; 运动(Motion);

机译：Models;heart valve effects;Motion;simulation;运动(Motion);

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1. Numerical simulation of cardiovascular dynamics with healthy and diseased heart valves. [J] . Korakianitis T, Shi Y Journal of Biomechanics . 2006,第11期

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Numerical simulation of cardiovascular dynamics with healthy and diseased heart valves.

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