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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >The effect of calcium phosphate bone substitute on defect resolution around a rough-surfaced dental implants in dogs.
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The effect of calcium phosphate bone substitute on defect resolution around a rough-surfaced dental implants in dogs.

机译：磷酸钙骨替代物对狗表面粗糙的牙科植入物周围的缺损分辨力的影响。

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Gap defects often exist around dental implants due to morphological differences between the natural tooth extraction socket and the dental implant. Techniques that can resolve such gap defects include implant surface modification and filling of the defects with bone substitutes. Modified surfaces are generally more effective in this regard than smooth surfaces. Favorable results have also been reported using bone substitutes. This study evaluated the effectiveness of a calcium phosphate (CaP) bone substitute for resolving gap defects around implant surfaces that have been treated with grit blasting and thermal etching. Implants were placed in edentulous areas in four mongrel dogs. Gap defects with a diameter of 2 mm were prepared surgically around the dental implants. These defects were either filled with CaP bone substitute (experimental group) or left unfilled (control group). Defects were evaluated after 8 and 16 weeks of healing. Block specimens were fixed, sectioned, and stained with hematoxylin and eosin. Histometric measurements revealed that healing in gap defects that had been filled with CaP bone substitute proceeded until 16 weeks. Total CaP degradation seemed to occur at between 4 and 8 weeks of healing. In conclusion, a more complete defect resolution was observed in gap defects filled with CaP bone substitute after 16 weeks than after 8 weeks of healing. The beneficial effects of filling in 2-mm gap defects around implants were attributed to the use of CaP bone substitute.
机译：由于天然拔牙窝和牙科植入物之间的形态差异，在牙科植入物周围经常存在间隙缺陷。可以解决此类间隙缺陷的技术包括植入物表面修饰和用骨替代物填充缺陷。在这方面，改性表面通常比光滑表面更有效。还报道了使用骨替代物的良好结果。这项研究评估了磷酸钙（CaP）骨替代物用于解决经过喷砂和热蚀刻处理的植入物表面周围间隙缺陷的有效性。将植入物放在四只杂种狗的无牙区域。通过手术在牙科植入物周围准备直径为2毫米的间隙缺损。这些缺损要么用CaP骨替代物填充（实验组），要么不填充（对照组）。在愈合8周和16周后评估缺陷。将块状样品固定，切片并用苏木精和曙红染色。直方图测量显示，用CaP骨替代物填充的间隙缺损的愈合持续到16周。全部CaP降解似乎在愈合的4到8周之间发生。总之，在愈合后16周，与用药8周后相比，在用CaP骨替代物填充的间隙缺损中观察到了更加完整的缺损。填补种植体周围2毫米间隙缺损的有益效果归因于使用CaP骨替代物。

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