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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Physicochemical properties and in vitro biocompatibility of a hydraulic calcium silicate/tricalcium aluminate cement for endodontic use.
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Physicochemical properties and in vitro biocompatibility of a hydraulic calcium silicate/tricalcium aluminate cement for endodontic use.

机译:牙髓用液压硅酸钙/铝酸三钙水泥的理化特性和体外生物相容性。

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摘要

This study sought to prepare a calcium silicate cement (CSC) with varying additions of tricalcium aluminate (Ca(3)Al(2)O(6), C(3)A), and to find an optimal amount of C(3)A by evaluating the effect of C(3)A on the physicochemical and in vitro biological properties of the CS/C(3)A cement. The results indicated that the addition of C(3)A into CSC reduced the setting time and improved the compressive strength especially at the early stage of setting. However, the 15% C(3)A was too much for the CS/C(3)A system and did harm to its strength development. Furthermore, the CS/C(3)A cement was bioactive and biocompatible in vitro, and had a stimulatory effect on the cell growth, when the content of C(3)A was 5 or 10%. When compared with the commercially available Dycal(?), the CS/C(3)A cement was notably more compatible with the human dental pulp cells. Therefore, the CS/C(3)A cement with 5-10% C(3)A produced the best compromise between setting and in vitro biological properties, and may be a promising candidate for endodontic use.
机译:这项研究试图制备具有不同添加量的铝酸三钙(Ca(3)Al(2)O(6),C(3)A)的硅酸钙水泥(CSC),并找到最佳量的C(3)通过评估C(3)A对CS / C(3)A水泥的物理化学和体外生物学特性的影响来确定A。结果表明,在CSC中添加C(3)A可以减少凝固时间,提高抗压强度,特别是在凝固初期。但是,对于CS / C(3)A系统而言,15%的C(3)A太高了,并损害了它的强度发展。此外,CS / C(3)A水泥在体外具有生物活性和生物相容性,当C(3)A的含量为5%或10%时,对细胞生长具有刺激作用。与市售的Dycal(α)相比,CS / C(3)A水泥与人牙髓细胞的相容性更强。因此,具有5-10%C(3)A的CS / C(3)A水泥在凝结和体外生物学特性之间产生了最佳折衷,并且可能是牙髓治疗的有希望的候选者。

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