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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Clinical and Histological Findings in Guided Bone Regeneration (GBR) Around Titanium Dental Implants with Autogeneous Bone Chips Using a New Resorbable Membrane
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Clinical and Histological Findings in Guided Bone Regeneration (GBR) Around Titanium Dental Implants with Autogeneous Bone Chips Using a New Resorbable Membrane

机译：使用新型可吸收膜的自体骨芯片在钛牙种植体周围引导性骨再生（GBR）的临床和组织学发现

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The aim of this study was to test the value of a polydioxanon-membrane (PDS, Ethicon, Norderstedt, Germany) in combination with autogenous bone as a spacer for guided bone regeneration of denuded implant surfaces in comparison to simple augmentation. Altogether, in 8 Beagle dogs of 12 months, the three mandibular premolars were extracted on both sides and, after an uneventful healing of the extraction sockets in each mandibular site, two seize defined bone defects were produced. The defects were 7 mm long, had a vertical extension of 7 mm, and were 7 mm deep. These also included, therefore, the resection of the lingual cortical bone wall. In the center of all these 32 bone defects, Branemark fixtures with a diameter of 3 mm and a length of 10 mm were implanted. Every implant was primarily stable due to the fixation in the native bone under the created defects. In each mandible site, one bone defect was filled with autologous bone resulting from the previous defect preparation. Half of the defects were covered with a PDS membrane, and the other half were covered only by the relocation of the mucoperiosteal flap. During the observation period of 90-180 days, continuous clinical and radiological controls were executed. Aside from the observed clinical healing problems in the test sites, such as exposure of the membranes and serious inflammatory reactions, the histological and radiological results of the control group regard. mg bone regeneration were superior to these of the test group, which were valid also for the subgroups with or without autologous bone fillings.
机译：这项研究的目的是测试聚二恶烷膜（PDS，Ethicon，Norderstedt，德国）与自体骨相结合作为隔离种植体表面引导骨再生的垫片的价值，与单纯增强相比。总共在8个12个月的Beagle犬中，从两侧提取了三个下颌前磨牙，并且在每个下颌部位的拔牙窝恢复正常之后，产生了两个抓住的明确的骨缺损。缺陷长7毫米，垂直延伸7毫米，深7毫米。因此，这些还包括舌侧皮质骨壁的切除。在所有这32个骨缺损的中心，植入直径3 mm，长度10 mm的Branemark固定器。每个植入物由于在产生的缺损下固定在天然骨中而基本上是稳定的。在每个下颌骨部位，一个骨头缺损中充满了由先前的缺损准备产生的自体骨头。缺损的一半用PDS膜覆盖，另一半仅通过粘膜骨膜瓣的移位来覆盖。在90-180天的观察期内，进行了连续的临床和放射控制。除了在测试部位观察到的临床愈合问题外，例如膜的暴露和严重的炎症反应，还要考虑对照组的组织学和放射学结果。 mg的骨再生优于测试组，对于有或没有自体骨充填的亚组也有效。

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