...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Erroneous aluminum and cobalt tissue concentrations from using formalin
【24h】

Erroneous aluminum and cobalt tissue concentrations from using formalin

机译：使用福尔马林导致铝和钴组织浓度错误

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Because of the liberation of metal particles from orthopedic implants, concerns have been voiced about their long-term safety. To document the presence and measure the amount of metal in periprosthetic tissues, many reports have analyzed tissue specimens obtained from revision surgery. Some report the inclusion of formalin in tissue processing. However, the unavailability of any medical-grade formalin solution with a known metal content raises the suspicion of sample contamination. The purpose of this study was to measure the concentration of the metals in the formalin found in common orthopedic alloys and to assess this chemical's role in removing metal ions from tissue samples. To do this, tissues with known metal concentrations of cobalt and aluminum were mixed with formalin, and the differences in the formalin and tissue concentrations of these elements were evaluated. Tissue and formalin samples were tested prior to and immediately after their mixing and then at three 10-day intervals. At the end of the study additional unmixed samples of formalin and tissue for both metals were tested to ensure there had been no contamination. Both cobalt and aluminum were found in off-the-shelf formalin, with observed decreases in tissue metal concentration and increases in formalin metal concentration.
机译：由于从整形外科植入物中释放出金属颗粒，人们一直对其长期安全性表示担忧。为了记录假体周围组织中金属的含量并测量其含量，许多报告分析了翻修手术获得的组织标本。一些报告称福尔马林在组织加工中包括在内。但是，无法获得具有已知金属含量的任何医用级福尔马林溶液，这增加了对样品污染的怀疑。这项研究的目的是测量常见骨科合金中福尔马林中金属的浓度，并评估该化学物质在从组织样本中去除金属离子中的作用。为此，将具有已知金属浓度的钴和铝的组织与福尔马林混合，并评估福尔马林和这些元素的组织浓度的差异。在混合之前和之后立即测试组织和福尔马林样品，然后每三个10天间隔一次。在研究结束时，对两种金属的其他未混合福尔马林和组织样品进行了测试，以确保没有污染。现成的福尔马林中发现了钴和铝，观察到组织金属浓度降低而福尔马林金属浓度增加。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号