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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Mechanical properties of coagulated albumin and failure mechanisms of liver repaired with the use of an argon-beam coagulator with albumin.
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Mechanical properties of coagulated albumin and failure mechanisms of liver repaired with the use of an argon-beam coagulator with albumin.

机译：凝结白蛋白的机械性能和肝衰竭机制可以通过使用带有白蛋白的氩束凝结器来修复。

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摘要

Hemostasis in the traumatized liver has been achieved by thermally denaturing topically applied albumin. In this article, the mechanical properties of liver and denatured albumin (solder) were measured, and the failure methods of liver repaired with albumin were identified. The ultimate tensile strength and Young's modulus were measured for healthy liver (N = 20) and thermally damaged liver (N = 20). The ultimate tensile strength and Young's modulus were measured for three concentrations of coagulated albumin (25, 38, and 53%) in a single layer and for two layers of denatured 38% albumin. Failure under tension of argon-beam coagulator soldered liver on the parenchymal surface (N = 30) with 38% albumin in two layers had a 70% occurrence for tearing at a mean stress of 39 kPa and a 23% occurrence for shearing at a mean stress of 7 kPa. Liver repaired on the interior surface (N = 11) failed in tension by tearing (64%) at a mean stress of 34 kPa and by shearing (36%) at a mean stress of 6 kPa. Argon-beam coagulator soldering with 38% albumin took 6 s/cm(2) for two layers of solder and gave the best balance of usability, strength, and matching of mechanical properties with those of the liver.
机译：通过热变性局部施用的白蛋白已经达到了受创伤的肝脏中的止血作用。本文测定了肝脏和变性白蛋白（焊料）的力学性能，并确定了用白蛋白修复的肝脏的失败方法。测量了健康肝脏（N = 20）和热损伤肝脏（N = 20）的极限抗拉强度和杨氏模量。对于单层中的三个浓度的凝结白蛋白（25％，38％和53％）和两层变性的38％的白蛋白，测量了极限拉伸强度和杨氏模量。两层中含38％白蛋白的氩气束凝结器焊接肝在实质表面（N = 30）的拉伸作用下失效时，在39 kPa的平均应力下发生撕裂的发生率为70％，在平均应力下的剪切发生率为23％应力为7 kPa。内表面修复的肝脏（N = 11）在平均应力为34 kPa时撕裂（64％），在平均应力为6 kPa时剪断（36％），从而使拉伸失败。用38％的白蛋白进行氩气束凝结剂焊接，两层焊料的焊接时间为6 s / cm（2），并且在可用性，强度和机械性能与肝脏的机械性能之间达到了最佳平衡。

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