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首页> 外文期刊>Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research >Men and women in space: Bone loss and kidney stone risk after long-duration spaceflight
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Men and women in space: Bone loss and kidney stone risk after long-duration spaceflight

机译：太空中的男女：长期太空飞行后，骨质流失和肾结石的风险

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Bone loss, a key concern for long-duration space travelers, is typically considered a female issue. The number of women who have flown long-duration space missions is now great enough to allow a quantitative comparison of changes in bone and renal stone risk by sex. Participants were 42 astronauts (33 men and 9 women) on long-duration missions to the International Space Station. Bone mineral density (by dual-energy X-ray absorptiometry) and biochemical markers of bone metabolism (from blood and urine samples) were evaluated before and after flight. Data were analyzed in two groups, based on available resistance exercise equipment. Missions were 49 to 215 days in duration, flown between 2000 and 2012. The bone density response to spaceflight was the same for men and women in both exercise groups. The bone mineral density response to flight was the same for men and women, and the typical decrease in bone mineral density (whole body and/or regional) after flight was not observed for either sex for those using an advanced resistive exercise device. Biochemical markers of bone formation and resorption responded similarly in male and female astronauts. The response of urinary supersaturation risk to spaceflight was not significantly different between men and women, although risks were typically increased after flight in both groups, and risks were greater in men than in women before and after flight. The responses of men and women to spaceflight with respect to these measures of bone health were not different.
机译：骨骼丢失是长时间太空旅行者的关键问题，通常被认为是女性问题。现在，执行长期太空任务的女性人数已经足够多，可以定量比较性别对骨和肾结石风险的影响。参加此次国际空间站长期任务的42名宇航员（33名男性和9名女性）。在飞行之前和之后，评估了骨矿物质密度（通过双能X线骨密度仪）和骨代谢的生化指标（来自血液和尿液样本）。根据可用的阻力锻炼设备，将数据分为两组。任务时间为49至215天，飞行时间为2000年至2012年。两个运动组的男女对航天的骨密度反应相同。男性和女性对飞行的骨矿物质密度反应相同，对于使用高级阻力锻炼装置的男女，飞行后的骨矿物质密度（全身和/或局部）均未观察到典型的下降。男性和女性宇航员对骨形成和吸收的生化标志物的反应相似。男女之间的尿过饱和风险对航天反应的反应没有显着差异，尽管两组的风险通常都在飞行后增加，并且飞行前后男性的风险都大于女性。对于这些骨骼健康指标，男人和女人对太空飞行的反应没有不同。

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