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首页> 外文期刊>Journal of Biomolecular Structure and Dynamics >Nucleosome units and hidden periodicities in DNA sequences.
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Nucleosome units and hidden periodicities in DNA sequences.

机译:DNA序列中的核小体单位和隐藏的周期性。

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摘要

The relationship between the hidden periodicities in DNA sequences and the nucleosome units is investigated. It is shown that in the vicinity of lengths of about 200 bases there are statistically significant periodicities which remain approximately universal for exon-intron sequences both in the different genes and the different eukaryotic species. The additional analysis displays, nevertheless, that these approximately coincident universal periodicities can be generated by a variety of mechanisms. The relevance of the features observed to the structure of chromatin is discussed.
机译:研究了DNA序列中隐藏的周期性与核小体单位之间的关系。结果表明,在大约200个碱基的长度附近,具有统计上显着的周期性,在不同的基因和不同的真核生物种中,该频率对于外显子-内含子序列都保持大致通用。尽管如此,附加分析显示,这些近似一致的通用周期可以通过多种机制生成。讨论了所观察到的特征与染色质结构的相关性。

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