...
首页> 外文期刊>Journal of Biomolecular Structure and Dynamics >Structural Features in the Model of a Thermostable and Stress-resistant Protein, SP1 from aspen.
【24h】

Structural Features in the Model of a Thermostable and Stress-resistant Protein, SP1 from aspen.

机译:白杨的耐热和抗逆蛋白SP1模型中的结构特征。

获取原文
获取原文并翻译 | 示例
           

摘要

A three dimensional theoretical model of SP1 (stable protein 1), which is resistant to high temperature and biotic-stresses, is presented here. The model was generated by the application of homology modeling technique. The conformational rigidity imparted to the fold by the presence of hydrogen-bonded, C(5), C(7), C(10) and C(13) structures in the loop regions, multiple aromatic - aromatic interactions at the protein interior and on the surface, in addition to salt-links and hydrogen-bonds are primarily the major factors, responsible for the increased stability of protein. The putative protein family is characterized by motifs, E-x(0,1)-L-x-[AEGQS] and V-x(2,3)-L-x-[ADEGST] and the active site in the tertiary structure is formed by conserved aromatic and isoleucine clusters.
机译:在此介绍了一种能够抵抗高温和生物胁迫的SP1(稳定蛋白1)的三维理论模型。该模型是通过应用同源建模技术生成的。环状区域中存在氢键,C(5),C(7),C(10)和C(13)结构,蛋白质内部和表面的多个芳香族-芳香族相互作用,从而赋予折叠折叠构象刚性在表面上,除盐键和氢键外,主要是导致蛋白质稳定性提高的主要因素。推定的蛋白质家族的特征是基序,Ex(0,1)-Lx- [AEGQS]和Vx(2,3)-Lx- [ADEGST],三级结构中的活性位点由保守的芳香族和异亮氨酸簇形成。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号